Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1948891..1950111 Replicon chromosome
Accession NZ_CP119366
Organism Pseudomonas sp. CBSPBW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D91_RS08950 Protein ID WP_258344820.1
Coordinates 1949536..1950111 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D91_RS08945 Protein ID WP_258344821.1
Coordinates 1948891..1949448 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D91_RS08925 (P0D91_08925) 1944789..1945445 + 657 WP_258344824.1 RraA family protein -
P0D91_RS08930 (P0D91_08930) 1945442..1946683 + 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D91_RS08935 (P0D91_08935) 1946768..1948105 + 1338 WP_256576936.1 MFS transporter -
P0D91_RS08940 (P0D91_08940) 1948131..1948793 + 663 WP_258344822.1 RraA family protein -
P0D91_RS08945 (P0D91_08945) 1948891..1949448 + 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D91_RS08950 (P0D91_08950) 1949536..1950111 + 576 WP_258344820.1 HD domain-containing protein Toxin
P0D91_RS08955 (P0D91_08955) 1950118..1952331 - 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D91_RS08960 (P0D91_08960) 1952328..1952852 - 525 WP_258344818.1 DUF2531 family protein -
P0D91_RS08965 (P0D91_08965) 1952849..1953460 - 612 WP_258344817.1 type II secretion system protein GspM -
P0D91_RS08970 (P0D91_08970) 1953435..1954474 - 1040 Protein_1790 PilN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274022 WP_258344820.1 NZ_CP119366:1949536-1950111 [Pseudomonas sp. CBSPBW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274022 WP_258344821.1 NZ_CP119366:1948891-1949448 [Pseudomonas sp. CBSPBW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References