Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 1948891..1950111 | Replicon | chromosome |
| Accession | NZ_CP119366 | ||
| Organism | Pseudomonas sp. CBSPBW29 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | P0D91_RS08950 | Protein ID | WP_258344820.1 |
| Coordinates | 1949536..1950111 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | P0D91_RS08945 | Protein ID | WP_258344821.1 |
| Coordinates | 1948891..1949448 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P0D91_RS08925 (P0D91_08925) | 1944789..1945445 | + | 657 | WP_258344824.1 | RraA family protein | - |
| P0D91_RS08930 (P0D91_08930) | 1945442..1946683 | + | 1242 | WP_275708835.1 | pyridoxal phosphate-dependent aminotransferase | - |
| P0D91_RS08935 (P0D91_08935) | 1946768..1948105 | + | 1338 | WP_256576936.1 | MFS transporter | - |
| P0D91_RS08940 (P0D91_08940) | 1948131..1948793 | + | 663 | WP_258344822.1 | RraA family protein | - |
| P0D91_RS08945 (P0D91_08945) | 1948891..1949448 | + | 558 | WP_258344821.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| P0D91_RS08950 (P0D91_08950) | 1949536..1950111 | + | 576 | WP_258344820.1 | HD domain-containing protein | Toxin |
| P0D91_RS08955 (P0D91_08955) | 1950118..1952331 | - | 2214 | WP_258344819.1 | type II secretion system secretin GspD | - |
| P0D91_RS08960 (P0D91_08960) | 1952328..1952852 | - | 525 | WP_258344818.1 | DUF2531 family protein | - |
| P0D91_RS08965 (P0D91_08965) | 1952849..1953460 | - | 612 | WP_258344817.1 | type II secretion system protein GspM | - |
| P0D91_RS08970 (P0D91_08970) | 1953435..1954474 | - | 1040 | Protein_1790 | PilN domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21642.58 Da Isoelectric Point: 4.9800
>T274022 WP_258344820.1 NZ_CP119366:1949536-1950111 [Pseudomonas sp. CBSPBW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR
Download Length: 576 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20596.80 Da Isoelectric Point: 7.8767
>AT274022 WP_258344821.1 NZ_CP119366:1948891-1949448 [Pseudomonas sp. CBSPBW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|