273989

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 938717..939194 Replicon chromosome
Accession NZ_CP119340
Organism Staphylococcus aureus strain N28CSA05

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag P1A15_RS04595 Protein ID WP_000052076.1
Coordinates 938717..938905 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag P1A15_RS04600 Protein ID WP_001059690.1
Coordinates 938934..939194 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A15_RS04565 (P1A15_04565) 934752..935228 + 477 WP_000824477.1 hypothetical protein -
P1A15_RS04570 (P1A15_04570) 935569..936255 + 687 WP_001641381.1 thermonuclease family protein -
P1A15_RS04575 (P1A15_04575) 936612..936812 + 201 WP_001059082.1 cold-shock protein -
P1A15_RS04580 (P1A15_04580) 937308..937526 - 219 WP_000005887.1 hypothetical protein -
P1A15_RS04585 (P1A15_04585) 937588..937872 - 285 WP_031590186.1 hypothetical protein -
P1A15_RS04590 (P1A15_04590) 937960..938529 - 570 WP_001106652.1 lipoprotein N-acylation protein LnsA -
P1A15_RS04595 (P1A15_04595) 938717..938905 - 189 WP_000052076.1 hypothetical protein Toxin
P1A15_RS04600 (P1A15_04600) 938934..939194 - 261 WP_001059690.1 hypothetical protein Antitoxin
P1A15_RS04605 (P1A15_04605) 939535..939738 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
P1A15_RS04610 (P1A15_04610) 939735..939971 - 237 WP_000368687.1 hypothetical protein -
P1A15_RS04615 (P1A15_04615) 940196..940777 + 582 WP_001140697.1 histidine phosphatase family protein -
P1A15_RS04620 (P1A15_04620) 940850..941467 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
P1A15_RS04625 (P1A15_04625) 941623..942117 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
P1A15_RS04630 (P1A15_04630) 942516..942938 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
P1A15_RS04635 (P1A15_04635) 943086..943802 + 717 WP_031589686.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T273989 WP_000052076.1 NZ_CP119340:c938905-938717 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT273989 WP_001059690.1 NZ_CP119340:c939194-938934 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References