Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1543064..1543209 Replicon chromosome
Accession NZ_CP119332
Organism Klebsiella pneumoniae strain CQ22WZ0036

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1543100..1543202 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1543064..1543209 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OMP07_RS07605 (OMP07_07605) 1538194..1540254 + 2061 WP_004151449.1 oligopeptidase B -
OMP07_RS07610 (OMP07_07610) 1540258..1540917 - 660 WP_002911407.1 exodeoxyribonuclease X -
OMP07_RS07615 (OMP07_07615) 1540996..1541226 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OMP07_RS07620 (OMP07_07620) 1541339..1541713 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OMP07_RS07625 (OMP07_07625) 1541717..1542586 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OMP07_RS07630 (OMP07_07630) 1542603..1542941 + 339 WP_002911404.1 YebY family protein -
- 1543064..1543209 - 146 - - Antitoxin
- 1543100..1543202 + 103 - - Toxin
OMP07_RS07635 (OMP07_07635) 1543577..1543720 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OMP07_RS07640 (OMP07_07640) 1543825..1544793 - 969 WP_004151446.1 VirK/YbjX family protein -
OMP07_RS07645 (OMP07_07645) 1544950..1545603 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OMP07_RS07650 (OMP07_07650) 1545600..1545791 - 192 WP_002911395.1 YebW family protein -
OMP07_RS07655 (OMP07_07655) 1545889..1546128 - 240 WP_002911393.1 YebV family protein -
OMP07_RS07660 (OMP07_07660) 1546244..1547677 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273957 NZ_CP119332:1543100-1543202 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT273957 NZ_CP119332:c1543209-1543064 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References