273952

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1013196..1013991 Replicon chromosome
Accession NZ_CP119327
Organism Staphylococcus sp. NRL 16/872

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag MT340_RS05020 Protein ID WP_243589016.1
Coordinates 1013818..1013991 (+) Length 58 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag MT340_RS05015 Protein ID WP_243589015.1
Coordinates 1013196..1013795 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT340_RS04995 (MT340_004995) 1009087..1010541 + 1455 WP_243589011.1 ABC transporter substrate-binding protein/permease -
MT340_RS05000 (MT340_005000) 1010534..1011256 + 723 WP_243589012.1 amino acid ABC transporter ATP-binding protein -
MT340_RS05005 (MT340_005005) 1011417..1012544 + 1128 WP_243589013.1 tRNA epoxyqueuosine(34) reductase QueG -
MT340_RS05010 (MT340_005010) 1012545..1013015 + 471 WP_243589014.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
MT340_RS05015 (MT340_005015) 1013196..1013795 + 600 WP_243589015.1 glucosamine-6-phosphate isomerase Antitoxin
MT340_RS05020 (MT340_005020) 1013818..1013991 + 174 WP_243589016.1 SAS053 family protein Toxin
MT340_RS05025 (MT340_005025) 1014172..1014564 + 393 WP_243589017.1 hypothetical protein -
MT340_RS05030 (MT340_005030) 1014701..1016086 + 1386 WP_243589018.1 class II fumarate hydratase -
MT340_RS05035 (MT340_005035) 1016149..1016970 - 822 WP_243603614.1 RluA family pseudouridine synthase -
MT340_RS05040 (MT340_005040) 1017182..1018297 + 1116 WP_243589020.1 GAF domain-containing sensor histidine kinase -
MT340_RS05045 (MT340_005045) 1018316..1018939 + 624 WP_243589021.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6726.17 Da        Isoelectric Point: 3.9487

>T273952 WP_243589016.1 NZ_CP119327:1013818-1013991 [Staphylococcus sp. NRL 16/872]
MSDKKETELNYHEEENAMVQDLDDLKELGKEMEQISEKNDEEKLNQSHDSDVRSDLD

Download         Length: 174 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22463.45 Da        Isoelectric Point: 4.8518

>AT273952 WP_243589015.1 NZ_CP119327:1013196-1013795 [Staphylococcus sp. NRL 16/872]
MAMNFKVFNDVDQVAQFTADIIRKQFNNNPTTIAGLHLERETAPVLDELKKDVDRNPVDFSQVNILDYDDNRSYYEALGV
PSGQIYPINLDDDATSLIDDKIKTKENKGKLILQVTSIDEKGSLNVNIRQGLMKAREVVLVITGGQKREFVKKLYEENGK
SSFEPADLKVHRMVTVVLDRAAAEGLPEDVKEYFTAHFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References