Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 867051..867562 Replicon chromosome
Accession NZ_CP119327
Organism Staphylococcus sp. NRL 16/872

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag MT340_RS04175 Protein ID WP_243588902.1
Coordinates 867356..867562 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag MT340_RS04170 Protein ID WP_103298014.1
Coordinates 867051..867344 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT340_RS04150 (MT340_004150) 862229..863101 + 873 WP_243588900.1 membrane protein insertase YidC -
MT340_RS04155 (MT340_004155) 863255..864571 + 1317 WP_243588819.1 ISL3 family transposase -
MT340_RS04160 (MT340_004160) 864661..865311 - 651 WP_243603599.1 HD domain-containing protein -
MT340_RS04165 (MT340_004165) 865378..866862 - 1485 WP_243588901.1 cardiolipin synthase -
MT340_RS04170 (MT340_004170) 867051..867344 + 294 WP_103298014.1 copper-sensing transcriptional repressor CsoR Antitoxin
MT340_RS04175 (MT340_004175) 867356..867562 + 207 WP_243588902.1 heavy-metal-associated domain-containing protein Toxin
MT340_RS04180 (MT340_004180) 867672..867809 + 138 WP_243588903.1 Lmo0850 family protein -
MT340_RS04185 (MT340_004185) 867854..869041 - 1188 WP_243588904.1 FtsW/RodA/SpoVE family cell cycle protein -
MT340_RS04190 (MT340_004190) 869472..870542 + 1071 WP_243588905.1 D-alanine--D-alanine ligase -
MT340_RS04195 (MT340_004195) 870558..871913 + 1356 WP_243588906.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 863255..864571 1316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(16-92)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7783.72 Da        Isoelectric Point: 4.2259

>T273950 WP_243588902.1 NZ_CP119327:867356-867562 [Staphylococcus sp. NRL 16/872]
MARSNVNIEGLNTNEQAEQLQHRLSQMIGVKEVIVSADYKIVEIEYETPTNLNSIEKEIYDDGFKVLN

Download         Length: 207 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11193.87 Da        Isoelectric Point: 6.4769

>AT273950 WP_103298014.1 NZ_CP119327:867051-867344 [Staphylococcus sp. NRL 16/872]
MSSEIHAHHSEQMKLNLKSRLNRIEGQVRAINRMIEDDVYCDDVLTQIRATRSALNSVATKLLDYHMKSCIMDKVNNGAQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References