273949

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 4675643..4676376 Replicon chromosome
Accession NZ_CP119319
Organism MAG: Kluyvera intermedia isolate MAG 4159

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag P0Y47_RS21580 Protein ID WP_279216165.1
Coordinates 4675643..4675972 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag P0Y47_RS21585 Protein ID WP_279216166.1
Coordinates 4676011..4676376 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0Y47_RS21560 (4670985) 4670985..4671995 - 1011 WP_279216162.1 ABC transporter substrate-binding protein -
P0Y47_RS21565 (4672008) 4672008..4674134 - 2127 WP_279216163.1 TonB-dependent siderophore receptor -
P0Y47_RS21570 (4674361) 4674361..4674783 - 423 WP_279216164.1 hypothetical protein -
P0Y47_RS21575 (4674941) 4674941..4675183 - 243 WP_153742334.1 DinI family protein -
P0Y47_RS21580 (4675643) 4675643..4675972 - 330 WP_279216165.1 TA system toxin CbtA family protein Toxin
P0Y47_RS21585 (4676011) 4676011..4676376 - 366 WP_279216166.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
P0Y47_RS21590 (4676402) 4676402..4676623 - 222 WP_032680445.1 DUF987 domain-containing protein -
P0Y47_RS21595 (4676620) 4676620..4677162 - 543 WP_279216167.1 DNA repair protein RadC -
P0Y47_RS21600 (4677175) 4677175..4677618 - 444 WP_279216168.1 antirestriction protein -
P0Y47_RS21605 (4677649) 4677649..4678473 - 825 WP_279216169.1 DUF932 domain-containing protein -
P0Y47_RS21610 (4679148) 4679148..4679987 - 840 WP_279216170.1 hypothetical protein -
P0Y47_RS21615 (4680073) 4680073..4680486 - 414 WP_279216171.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12406.21 Da        Isoelectric Point: 9.6273

>T273949 WP_279216165.1 NZ_CP119319:c4675972-4675643 [Kluyvera intermedia]
MQTISSHPTRATQPCLSPVEIWQRLLTHLLSQHYGLTLNDTPFSNKTTIQEHIDAGISLSDAVNFLVEKYGLIRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13553.35 Da        Isoelectric Point: 5.0950

>AT273949 WP_279216166.1 NZ_CP119319:c4676376-4676011 [Kluyvera intermedia]
MNNRSESGTKPENPACQLWGLKRAVTPCFGARLVQEGNRVHFLADRAGFHGAFSDDEALYLDQAFPLMLKQLELMLISGE
LNPRYQHCVTLYHNGLTCEADTLGSCGYVYIAIYPEQTEPQ

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References