273935

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1881945..1883453 Replicon chromosome
Accession NZ_CP119298
Organism Pseudomonas aeruginosa strain SNDPR-01

Toxin (Protein)


Gene name - Uniprot ID Q9HYX1
Locus tag PZ484_RS08755 Protein ID WP_003119682.1
Coordinates 1881945..1882532 (+) Length 196 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PZ484_RS08760 Protein ID WP_058132920.1
Coordinates 1882599..1883453 (+) Length 285 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ484_RS08750 1878200..1881679 - 3480 WP_003117605.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
PZ484_RS08755 1881945..1882532 + 588 WP_003119682.1 GNAT family protein Toxin
PZ484_RS08760 1882599..1883453 + 855 WP_058132920.1 AraC family transcriptional regulator Antitoxin
PZ484_RS08765 1883550..1885715 + 2166 WP_003115567.1 TonB-dependent receptor family protein -
PZ484_RS08770 1885890..1887764 + 1875 WP_070743140.1 MFS transporter -
PZ484_RS08775 1887825..1888034 - 210 WP_003115568.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(20-152)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-151)


Sequences

Toxin        


Download         Length: 196 a.a.        Molecular weight: 21901.23 Da        Isoelectric Point: 9.8676

>T273935 WP_003119682.1 NZ_CP119298:1881945-1882532 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG

Download         Length: 588 bp

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 31921.17 Da        Isoelectric Point: 7.3276

>AT273935 WP_058132920.1 NZ_CP119298:1882599-1883453 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHADSLETQTRWRETVLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE

Download         Length: 855 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 1YRE
PDB 8GXJ

Antitoxin

Source ID Structure

References