Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 989667..991134 Replicon chromosome
Accession NZ_CP119269
Organism Mycoplasmopsis bovis strain 1E2007VBG

Toxin (Protein)


Gene name abiEi Uniprot ID A0A2N8U3K6
Locus tag PY997_RS04240 Protein ID WP_014829995.1
Coordinates 990274..991134 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag PY997_RS04235 Protein ID WP_013456322.1
Coordinates 989667..990281 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY997_RS04210 (PY997_04210) 985610..986104 - 495 WP_275621898.1 variable surface lipoprotein -
PY997_RS04215 (PY997_04215) 986419..987672 - 1254 WP_275621899.1 variable surface lipoprotein -
PY997_RS04220 (PY997_04220) 987822..988025 + 204 WP_214461281.1 hypothetical protein -
PY997_RS04225 (PY997_04225) 988022..988654 - 633 WP_275621900.1 variable surface lipoprotein -
PY997_RS04230 (PY997_04230) 988830..989483 - 654 WP_275621901.1 variable surface lipoprotein -
PY997_RS04235 (PY997_04235) 989667..990281 + 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
PY997_RS04240 (PY997_04240) 990274..991134 + 861 WP_014829995.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PY997_RS04245 (PY997_04245) 991254..992150 + 897 WP_099620149.1 variable surface lipoprotein -
PY997_RS04250 (PY997_04250) 992309..993559 + 1251 WP_275621902.1 variable surface lipoprotein -
PY997_RS04255 (PY997_04255) 993735..994550 + 816 WP_275621903.1 variable surface lipoprotein -
PY997_RS04260 (PY997_04260) 994726..995382 + 657 WP_226060959.1 variable surface lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33280.36 Da        Isoelectric Point: 7.7731

>T273926 WP_014829995.1 NZ_CP119269:990274-991134 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT273926 WP_013456322.1 NZ_CP119269:989667-990281 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8U3K6

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References