Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1663161..1663800 Replicon chromosome
Accession NZ_CP119223
Organism Acinetobacter proteolyticus strain AP54

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PY247_RS07980 Protein ID WP_275573924.1
Coordinates 1663411..1663800 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A829HLN7
Locus tag PY247_RS07975 Protein ID WP_004657712.1
Coordinates 1663161..1663418 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY247_RS07950 (PY247_07950) 1658288..1658653 + 366 WP_004641032.1 50S ribosomal protein L17 -
PY247_RS07955 (PY247_07955) 1658814..1659380 + 567 WP_275573923.1 GNAT family N-acetyltransferase -
PY247_RS07960 (PY247_07960) 1659639..1661130 + 1492 Protein_1539 NAD(P)/FAD-dependent oxidoreductase -
PY247_RS07965 (PY247_07965) 1661255..1661755 + 501 WP_070076004.1 DUF2059 domain-containing protein -
PY247_RS07970 (PY247_07970) 1661800..1662972 - 1173 WP_004657709.1 acyl-CoA dehydrogenase family protein -
PY247_RS07975 (PY247_07975) 1663161..1663418 + 258 WP_004657712.1 succinate dehydrogenase assembly factor 2 Antitoxin
PY247_RS07980 (PY247_07980) 1663411..1663800 + 390 WP_275573924.1 hypothetical protein Toxin
PY247_RS07985 (PY247_07985) 1664008..1664214 + 207 WP_004657716.1 hypothetical protein -
PY247_RS07990 (PY247_07990) 1664573..1665714 + 1142 Protein_1545 hypothetical protein -
PY247_RS07995 (PY247_07995) 1665791..1666360 + 570 WP_004657724.1 rhombosortase -
PY247_RS08000 (PY247_08000) 1666516..1668726 + 2211 Protein_1547 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-126)

Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15694.61 Da        Isoelectric Point: 10.2640

>T273921 WP_275573924.1 NZ_CP119223:1663411-1663800 [Acinetobacter proteolyticus]
MANSAFELQYSRFALVLQLLLFLFIVGLVYSLVTFWWWLLSFAMMTIAWLSFLRQPQIRRFEYLDHQDCSFEFSDPTLKI
QRRQIVKILDHQLYIALYFSHKKHKPCIIWRDQLSHSQWKKLKVHAKLS

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10141.60 Da        Isoelectric Point: 4.4798

>AT273921 WP_004657712.1 NZ_CP119223:1663161-1663418 [Acinetobacter proteolyticus]
MSDEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRIELKEFILKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A829HLN7

References