Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1216268..1216905 Replicon chromosome
Accession NZ_CP119199
Organism Mycolicibacterium vanbaalenii strain L1I3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PXR06_RS05820 Protein ID WP_036370257.1
Coordinates 1216510..1216905 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PXR06_RS05815 Protein ID WP_036370259.1
Coordinates 1216268..1216513 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXR06_RS05795 1212088..1212627 + 540 WP_036370267.1 YceI family protein -
PXR06_RS05800 1212678..1214267 - 1590 WP_222880245.1 MFS transporter -
PXR06_RS05805 1214271..1215284 - 1014 WP_036370263.1 TIGR03617 family F420-dependent LLM class oxidoreductase -
PXR06_RS05810 1215307..1215915 - 609 WP_275572042.1 TetR/AcrR family transcriptional regulator -
PXR06_RS05815 1216268..1216513 + 246 WP_036370259.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PXR06_RS05820 1216510..1216905 + 396 WP_036370257.1 type II toxin-antitoxin system VapC family toxin Toxin
PXR06_RS05825 1216979..1220341 - 3363 WP_275572043.1 SbcC/MukB-like Walker B domain-containing protein -
PXR06_RS05830 1220334..1221023 - 690 WP_011778442.1 DUF4194 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Antitoxin VapB-like

(1-80)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14205.00 Da        Isoelectric Point: 4.5288

>T273917 WP_036370257.1 NZ_CP119199:1216510-1216905 [Mycolicibacterium vanbaalenii]
MIADSSAIIAILRDEDDAVDYARAVAAADVRRLSAASYLECGIVLDAQRDPVVSRALDELIDEAAMTIEPVTERQAKLAR
RAYAEFGRGSGHPARLNFGDCLSYALALDRREPLLWKGNDFGHTGIASALE

Download         Length: 396 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8973.09 Da        Isoelectric Point: 5.6706

>AT273917 WP_036370259.1 NZ_CP119199:1216268-1216513 [Mycolicibacterium vanbaalenii]
MALNIKDEKVHDAVKQLARLTGESQAQAVATAVQERLSRVQQDDLAERLLALGRRTAQRMTSATNDLDHGEMLYDDAGLP
R

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References