273914

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 4820437..4821004 Replicon chromosome
Accession NZ_CP119182
Organism Streptomyces caniscabiei strain ID03-3A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IHE65_RS21275 Protein ID WP_192361290.1
Coordinates 4820437..4820718 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IHE65_RS21280 Protein ID WP_225615251.1
Coordinates 4820723..4821004 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHE65_RS21255 (IHE65_21255) 4815584..4816483 + 900 WP_192361284.1 hypothetical protein -
IHE65_RS21260 (IHE65_21260) 4816528..4817151 - 624 WP_086786730.1 hypothetical protein -
IHE65_RS21265 (IHE65_21265) 4817851..4818783 + 933 WP_192361286.1 ester cyclase -
IHE65_RS21270 (IHE65_21270) 4818816..4820342 - 1527 WP_192361288.1 SDR family oxidoreductase -
IHE65_RS21275 (IHE65_21275) 4820437..4820718 - 282 WP_192361290.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHE65_RS21280 (IHE65_21280) 4820723..4821004 - 282 WP_225615251.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IHE65_RS21285 (IHE65_21285) 4821395..4822522 + 1128 WP_192361292.1 substrate-binding domain-containing protein -
IHE65_RS21290 (IHE65_21290) 4822626..4823402 + 777 WP_275874956.1 ATP-binding cassette domain-containing protein -
IHE65_RS21295 (IHE65_21295) 4823492..4824697 + 1206 WP_192332555.1 sugar ABC transporter permease -
IHE65_RS21300 (IHE65_21300) 4824746..4825351 - 606 WP_086805202.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10788.57 Da        Isoelectric Point: 10.6613

>T273914 WP_192361290.1 NZ_CP119182:c4820718-4820437 [Streptomyces caniscabiei]
MGYVTRFTPHAQRDMLKVPRPDALRILYRLAELQKAMDAGDTESFDIKALKGHSARWRFRVGDYRVVYTVEGGRLIVWVL
AVGNRREICRQVP

Download         Length: 282 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10489.68 Da        Isoelectric Point: 4.2042

>AT273914 WP_225615251.1 NZ_CP119182:c4821004-4820723 [Streptomyces caniscabiei]
MSEPVIESMAEVRSHLADVIDRAHREETPTIITRRGKQEAVVIDVQEYRRLREIAENAEEAWLNQLADEAESEGMEGSVS
LEEMAALLRTPQG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References