Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4553565..4554090 Replicon chromosome
Accession NZ_CP119182
Organism Streptomyces caniscabiei strain ID03-3A

Toxin (Protein)


Gene name relE Uniprot ID A0A927L4F6
Locus tag IHE65_RS20155 Protein ID WP_045558184.1
Coordinates 4553565..4553828 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IHE65_RS20160 Protein ID WP_086797547.1
Coordinates 4553821..4554090 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHE65_RS20125 (IHE65_20125) 4549023..4549544 - 522 WP_060887855.1 DUF2617 family protein -
IHE65_RS20130 (IHE65_20130) 4550041..4550430 - 390 WP_086797537.1 hypothetical protein -
IHE65_RS20135 (IHE65_20135) 4550564..4550773 - 210 WP_086797539.1 hypothetical protein -
IHE65_RS20140 (IHE65_20140) 4550923..4551162 - 240 WP_192334253.1 hypothetical protein -
IHE65_RS20145 (IHE65_20145) 4551490..4551948 + 459 WP_143674114.1 hypothetical protein -
IHE65_RS20150 (IHE65_20150) 4552062..4553294 + 1233 WP_192362546.1 pyridoxal phosphate-dependent aminotransferase -
IHE65_RS20155 (IHE65_20155) 4553565..4553828 - 264 WP_045558184.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHE65_RS20160 (IHE65_20160) 4553821..4554090 - 270 WP_086797547.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IHE65_RS20165 (IHE65_20165) 4554276..4554497 - 222 Protein_4006 hypothetical protein -
IHE65_RS20170 (IHE65_20170) 4554990..4555535 - 546 WP_045558187.1 YbjN domain-containing protein -
IHE65_RS20175 (IHE65_20175) 4555685..4558354 - 2670 WP_237277422.1 ATP-dependent chaperone ClpB -
IHE65_RS20180 (IHE65_20180) 4558496..4558909 + 414 WP_192362549.1 TIGR03618 family F420-dependent PPOX class oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-56)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10048.48 Da        Isoelectric Point: 8.5041

>T273913 WP_045558184.1 NZ_CP119182:c4553828-4553565 [Streptomyces caniscabiei]
VSEYRTVFRAEAQAELRKVPRDMALRILAKLTELESDPMGFNTTALVSQPDRRRLRVGDYRVIYTIDNGELVVWVVHVGH
RSTVYDT

Download         Length: 264 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10324.76 Da        Isoelectric Point: 4.7473

>AT273913 WP_086797547.1 NZ_CP119182:c4554090-4553821 [Streptomyces caniscabiei]
MTQSMPIESIRDVRAHLAEVVERADRDDVPTVITRRGKQVAAVVSIEVLRRYQEWEEREINRIIDERMANPAPGIPIEDI
MRETLARSE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References