Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011577..2011722 Replicon chromosome
Accession NZ_CP119174
Organism Klebsiella pneumoniae strain X-CRHVKP-130

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011613..2011715 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011577..2011722 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY995_RS09870 (PY995_09870) 2006707..2008767 + 2061 WP_004151449.1 oligopeptidase B -
PY995_RS09875 (PY995_09875) 2008771..2009430 - 660 WP_002911407.1 exodeoxyribonuclease X -
PY995_RS09880 (PY995_09880) 2009509..2009739 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PY995_RS09885 (PY995_09885) 2009852..2010226 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PY995_RS09890 (PY995_09890) 2010230..2011099 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
PY995_RS09895 (PY995_09895) 2011116..2011454 + 339 WP_002911404.1 YebY family protein -
- 2011577..2011722 - 146 - - Antitoxin
- 2011613..2011715 + 103 - - Toxin
PY995_RS09900 (PY995_09900) 2012090..2012233 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PY995_RS09905 (PY995_09905) 2012338..2013306 - 969 WP_004151446.1 VirK/YbjX family protein -
PY995_RS09910 (PY995_09910) 2013463..2014116 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
PY995_RS09915 (PY995_09915) 2014113..2014304 - 192 WP_002911395.1 YebW family protein -
PY995_RS09920 (PY995_09920) 2014402..2014641 - 240 WP_002911393.1 YebV family protein -
PY995_RS09925 (PY995_09925) 2014757..2016190 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273890 NZ_CP119174:2011613-2011715 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT273890 NZ_CP119174:c2011722-2011577 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References