Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 52491..53025 Replicon plasmid unnamed3
Accession NZ_CP119130
Organism Sphingobium sp. WTD-1

Toxin (Protein)


Gene name relE Uniprot ID W1S6F4
Locus tag N6H05_RS28060 Protein ID WP_004212931.1
Coordinates 52491..52772 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W1S0F5
Locus tag N6H05_RS28065 Protein ID WP_004212930.1
Coordinates 52759..53025 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6H05_RS28035 (N6H05_28035) 47668..49812 - 2145 WP_066269041.1 TonB-dependent siderophore receptor -
N6H05_RS28040 (N6H05_28040) 50107..50472 + 366 WP_004212937.1 hypothetical protein -
N6H05_RS28045 (N6H05_28045) 50510..50905 + 396 WP_062069509.1 hypothetical protein -
N6H05_RS28050 (N6H05_28050) 50902..51864 + 963 WP_004212934.1 tyrosine-type recombinase/integrase -
N6H05_RS28055 (N6H05_28055) 51861..52481 - 621 WP_037492298.1 histidine phosphatase family protein -
N6H05_RS28060 (N6H05_28060) 52491..52772 - 282 WP_004212931.1 type II toxin-antitoxin system YafQ family toxin Toxin
N6H05_RS28065 (N6H05_28065) 52759..53025 - 267 WP_004212930.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N6H05_RS28070 (N6H05_28070) 53429..54069 + 641 Protein_51 transcription elongation protein SprT -
N6H05_RS28075 (N6H05_28075) 54145..54798 + 654 WP_004212927.1 ParA family partition ATPase -
N6H05_RS28080 (N6H05_28080) 54795..55109 + 315 WP_066269038.1 hypothetical protein -
N6H05_RS28085 (N6H05_28085) 55782..56078 - 297 WP_257011066.1 GNAT family N-acetyltransferase -
N6H05_RS28090 (N6H05_28090) 56107..56706 - 600 WP_004212923.1 GNAT family N-acetyltransferase -
N6H05_RS28095 (N6H05_28095) 56703..57377 - 675 WP_080604539.1 YgjV family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..57709 57709


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-85)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10667.04 Da        Isoelectric Point: 8.0689

>T273813 WP_004212931.1 NZ_CP119130:c52772-52491 [Sphingobium sp. WTD-1]
MRTIDRSTRFKRDYKRESKGRHRATLDADLLPVLAALATDTPLDPKYRDHDLSGDWAGYRDCHVKPDLVLIYAKPDDETL
RLARLGSHSEVFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9448.88 Da        Isoelectric Point: 5.8213

>AT273813 WP_004212930.1 NZ_CP119130:c53025-52759 [Sphingobium sp. WTD-1]
MAVSDTYVRARIDNTTKERATAALGAMGLSISDAIRLLMLRIADERRLPFEVKVPNAATREAMAELAAGKGTKFASVDAL
MADLHADD

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W1S6F4

Antitoxin

Source ID Structure
AlphaFold DB W1S0F5

References