Detailed information of TA system TA273808

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-VagC
• Location: 3582618..3583256
• Replicon: chromosome
• Accession: NZ_CP119127
• Organism: Sphingobium sp. WTD-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: N6H05_RS17690
• Protein ID: WP_048938827.1
• Coordinates: 3582618..3583019 (-)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A0J9FLQ9
• Locus tag: N6H05_RS17695
• Protein ID: WP_010338822.1
• Coordinates: 3583023..3583256 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	3582618..3583019	-	402	-	-	Toxin
-	3583023..3583256	-	234	-	-	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

• SpoVT-AbrB domain (10-55)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 14437.62 Da
• Isoelectric Point: 4.7363

>T273808 WP_048938827.1 NZ_CP119127:c3583019-3582618 [Sphingobium sp. WTD-1]
MFLLDTNILSDLIRQPDGMVAHAIADVGEDAVATSIIVAGELRYGAEKRGSPRLKSKIEDLLSLIAVLPLKDDADACYGR
LRADLERRGTPIGANDMLIAAHALAIGATLVTDNIREFERVDGLQLVNWLRTT

Nucleotide

• Length: 402 bp

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8809.19 Da
• Isoelectric Point: 4.8723

>AT273808 WP_010338822.1 NZ_CP119127:c3583256-3583023 [Sphingobium sp. WTD-1]
MNLERHVKLFKNGRSQAVRIPREFELPGEDAIIRKEGSRLIIEPARPRSLLAVLKTWEPLDEEIGPIEDLPAEPVDI

Nucleotide

• Length: 234 bp

Structures

Antitoxin

• AlphaFold DB: A0A0J9FLQ9