Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2331500..2332040 Replicon chromosome
Accession NZ_CP119127
Organism Sphingobium sp. WTD-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N6H05_RS11640 Protein ID WP_284113981.1
Coordinates 2331750..2332040 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N6H05_RS11635 Protein ID WP_169860129.1
Coordinates 2331500..2331736 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6H05_RS11615 (N6H05_11615) 2326723..2327571 + 849 WP_010335536.1 ferredoxin--NADP reductase -
N6H05_RS11620 (N6H05_11620) 2327740..2329575 - 1836 WP_284113977.1 DUF885 family protein -
N6H05_RS11625 (N6H05_11625) 2329714..2330208 - 495 WP_284113978.1 hypothetical protein -
N6H05_RS11630 (N6H05_11630) 2330294..2331250 - 957 WP_284113979.1 hypothetical protein -
N6H05_RS11635 (N6H05_11635) 2331500..2331736 + 237 WP_169860129.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
N6H05_RS11640 (N6H05_11640) 2331750..2332040 + 291 WP_284113981.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N6H05_RS11645 (N6H05_11645) 2332180..2332626 - 447 WP_284113982.1 NfeD family protein -
N6H05_RS11650 (N6H05_11650) 2333153..2334124 - 972 WP_284113983.1 SPFH domain-containing protein -
N6H05_RS11655 (N6H05_11655) 2334202..2335017 + 816 WP_284114216.1 CoA ester lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10602.02 Da        Isoelectric Point: 8.0670

>T273807 WP_284113981.1 NZ_CP119127:2331750-2332040 [Sphingobium sp. WTD-1]
VKRLLFTPAAQAELSDIWDYSAATWGVDQADLYIDAIRDVCLALADGRRPGLPVDVRPGYRKASAGSHMIYYRNGGDHLA
IVRVLHGRQDTGRHLA

Download         Length: 291 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8344.28 Da        Isoelectric Point: 5.7834

>AT273807 WP_169860129.1 NZ_CP119127:2331500-2331736 [Sphingobium sp. WTD-1]
MARNTSVTIGDHFTRFISDQVQTGRYGSASDVVRAGLRLLEEREAQVQALQAALIAGEESGAATPFDFEAFKAAKRGG

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References