Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mbcAT/RES(toxin) |
| Location | 3575940..3576850 | Replicon | chromosome |
| Accession | NZ_CP119108 | ||
| Organism | Microbacterium sp. KACC 23027 | ||
Toxin (Protein)
| Gene name | mbcT | Uniprot ID | - |
| Locus tag | PU630_RS17030 | Protein ID | WP_275278248.1 |
| Coordinates | 3576290..3576850 (+) | Length | 187 a.a. |
Antitoxin (Protein)
| Gene name | mbcA | Uniprot ID | - |
| Locus tag | PU630_RS17025 | Protein ID | WP_275278247.1 |
| Coordinates | 3575940..3576293 (+) | Length | 118 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PU630_RS17005 (PU630_17005) | 3571567..3572211 | + | 645 | WP_275278243.1 | hypothetical protein | - |
| PU630_RS17010 (PU630_17010) | 3572892..3573764 | - | 873 | WP_275278244.1 | reverse transcriptase family protein | - |
| PU630_RS17015 (PU630_17015) | 3573922..3574665 | - | 744 | WP_275278245.1 | hypothetical protein | - |
| PU630_RS17020 (PU630_17020) | 3574711..3575865 | - | 1155 | WP_275278246.1 | hypothetical protein | - |
| PU630_RS17025 (PU630_17025) | 3575940..3576293 | + | 354 | WP_275278247.1 | DUF2384 domain-containing protein | Antitoxin |
| PU630_RS17030 (PU630_17030) | 3576290..3576850 | + | 561 | WP_275278248.1 | RES domain-containing protein | Toxin |
| PU630_RS17035 (PU630_17035) | 3576996..3577154 | - | 159 | WP_275278249.1 | hypothetical protein | - |
| PU630_RS17040 (PU630_17040) | 3577534..3578907 | - | 1374 | WP_275278250.1 | replicative DNA helicase | - |
| PU630_RS17045 (PU630_17045) | 3579378..3579728 | - | 351 | WP_275278251.1 | nuclear transport factor 2 family protein | - |
| PU630_RS17050 (PU630_17050) | 3579746..3580234 | - | 489 | WP_275278252.1 | carboxymuconolactone decarboxylase family protein | - |
| PU630_RS17055 (PU630_17055) | 3580305..3581168 | + | 864 | WP_275278253.1 | LysR family transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 187 a.a. Molecular weight: 19782.30 Da Isoelectric Point: 4.8083
>T273753 WP_275278248.1 NZ_CP119108:3576290-3576850 [Microbacterium sp. KACC 23027]
VTGLDEELVQHVDQLGSAGWTSTTHRYTAARRDPLSGAGARLFGGRWNPKDIFATIYLAQPLAACLGEVERTAKSQSTTP
DVLLRASYTLHEINVTNLPVLDLRDEHALAHVGLTLADISDPDWTACQAVGNAAWFLGLGGVLAPSATEEGVVLAAFEAR
IVGHLTVAKSEPLTPELFETLRAGTA
VTGLDEELVQHVDQLGSAGWTSTTHRYTAARRDPLSGAGARLFGGRWNPKDIFATIYLAQPLAACLGEVERTAKSQSTTP
DVLLRASYTLHEINVTNLPVLDLRDEHALAHVGLTLADISDPDWTACQAVGNAAWFLGLGGVLAPSATEEGVVLAAFEAR
IVGHLTVAKSEPLTPELFETLRAGTA
Download Length: 561 bp
Antitoxin
Download Length: 118 a.a. Molecular weight: 12622.39 Da Isoelectric Point: 5.5510
>AT273753 WP_275278247.1 NZ_CP119108:3575940-3576293 [Microbacterium sp. KACC 23027]
MSTAVARGALAQKVADIIDHLGLTQEEVGEIVDASARSVARWSSGEVVPQRLNKQRLLELAYVAQAVAEILPADNANVWI
HTPNRLLAHDTPAQRIHAGAYRDVLNLIEAIAEGIVV
MSTAVARGALAQKVADIIDHLGLTQEEVGEIVDASARSVARWSSGEVVPQRLNKQRLLELAYVAQAVAEILPADNANVWI
HTPNRLLAHDTPAQRIHAGAYRDVLNLIEAIAEGIVV
Download Length: 354 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|