Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpK-mazE/PemK(toxin)
Location 3117694..3118274 Replicon chromosome
Accession NZ_CP119108
Organism Microbacterium sp. KACC 23027

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag PU630_RS14770 Protein ID WP_275280115.1
Coordinates 3117694..3118017 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PU630_RS14775 Protein ID WP_275277818.1
Coordinates 3118035..3118274 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU630_RS14750 (PU630_14750) 3113755..3114444 - 690 WP_275277814.1 TetR/AcrR family transcriptional regulator -
PU630_RS14755 (PU630_14755) 3114626..3116242 + 1617 WP_275277815.1 FAD-binding oxidoreductase -
PU630_RS14760 (PU630_14760) 3116253..3116672 + 420 WP_275277816.1 VOC family protein -
PU630_RS14765 (PU630_14765) 3116890..3117657 + 768 WP_275277817.1 cyclase family protein -
PU630_RS14770 (PU630_14770) 3117694..3118017 - 324 WP_275280115.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PU630_RS14775 (PU630_14775) 3118035..3118274 - 240 WP_275277818.1 CopG family transcriptional regulator Antitoxin
PU630_RS14780 (PU630_14780) 3118461..3118754 + 294 WP_275277819.1 putative quinol monooxygenase -
PU630_RS14785 (PU630_14785) 3118756..3119724 + 969 WP_275277820.1 fumarylacetoacetate hydrolase family protein -
PU630_RS14790 (PU630_14790) 3119913..3120629 + 717 WP_275277821.1 IMP cyclohydrolase -
PU630_RS14795 (PU630_14795) 3120661..3121239 - 579 WP_275277822.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-107)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11195.94 Da        Isoelectric Point: 4.4013

>T273750 WP_275280115.1 NZ_CP119108:c3118017-3117694 [Microbacterium sp. KACC 23027]
VWVDFGEPRGSEPGKVRPAVILQDDWLLASSIATVVVVPLTSNTRLAAFPGNVLIPSEASGLEKDSVAVVSQIGPVSREY
IVPYPVGALANYLLSDVAAGVRLVIGL

Download         Length: 324 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9022.02 Da        Isoelectric Point: 4.8894

>AT273750 WP_275277818.1 NZ_CP119108:c3118274-3118035 [Microbacterium sp. KACC 23027]
MKTAISVPDGDFERFERTARKHGMNRSEFYRLAAQKLADELEGESELTAIANDVIERVGQPADAEFLRESHRAIRGTEW

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References