273749

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3042622..3043325 Replicon chromosome
Accession NZ_CP119108
Organism Microbacterium sp. KACC 23027

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PU630_RS14410 Protein ID WP_275277748.1
Coordinates 3042622..3043026 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PU630_RS14415 Protein ID WP_275277749.1
Coordinates 3043023..3043325 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU630_RS14385 (PU630_14385) 3037630..3038634 - 1005 WP_275277743.1 amidohydrolase family protein -
PU630_RS14390 (PU630_14390) 3038631..3039224 - 594 WP_275277744.1 TetR/AcrR family transcriptional regulator -
PU630_RS14395 (PU630_14395) 3039224..3040342 - 1119 WP_275277745.1 LLM class flavin-dependent oxidoreductase -
PU630_RS14400 (PU630_14400) 3040371..3041690 - 1320 WP_275277746.1 MFS transporter -
PU630_RS14405 (PU630_14405) 3041858..3042625 - 768 WP_275277747.1 IclR family transcriptional regulator C-terminal domain-containing protein -
PU630_RS14410 (PU630_14410) 3042622..3043026 - 405 WP_275277748.1 type II toxin-antitoxin system VapC family toxin Toxin
PU630_RS14415 (PU630_14415) 3043023..3043325 - 303 WP_275277749.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PU630_RS14420 (PU630_14420) 3043422..3044597 - 1176 WP_275277750.1 thiolase family protein -
PU630_RS14425 (PU630_14425) 3044600..3045274 - 675 WP_275277751.1 3-oxoacid CoA-transferase subunit B -
PU630_RS14430 (PU630_14430) 3045271..3046026 - 756 WP_275277752.1 3-oxoacid CoA-transferase subunit A -
PU630_RS14435 (PU630_14435) 3046216..3047439 + 1224 WP_275277753.1 cobalamin-independent methionine synthase II family protein -
PU630_RS14440 (PU630_14440) 3047864..3048250 - 387 WP_275277754.1 4-carboxymuconolactone decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-99)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14284.96 Da        Isoelectric Point: 4.3047

>T273749 WP_275277748.1 NZ_CP119108:c3043026-3042622 [Microbacterium sp. KACC 23027]
VIVDTSALIAVMEDEPQGAAIRRLLSDYGGRISAATLVEARMVAFGKGGPAAVRELDGLIRRARLDVAAVDVESADVATG
AFFAYGRGSGHPARLNFGDTFSYALAYIENDPLLYVGDDFSHTDIRSALEEYGE

Download         Length: 405 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11483.76 Da        Isoelectric Point: 5.6274

>AT273749 WP_275277749.1 NZ_CP119108:c3043325-3043023 [Microbacterium sp. KACC 23027]
MSLNIKNERTHALVRELAERTGMSQTSAVESAVRLRLEQLNAAEQHTGRPAPRYSPEEAERRLKDIERIAEHFRSITTAE
QREAMSDHGDWLYDEQGLPV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References