Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4719586..4720248 Replicon chromosome
Accession NZ_CP119083
Organism Telluria chitinolytica strain ACM 3522

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PX653_RS20885 Protein ID WP_277414636.1
Coordinates 4719586..4720035 (-) Length 150 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PX653_RS20890 Protein ID WP_277418626.1
Coordinates 4720042..4720248 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PX653_RS20870 (PX653_20870) 4716040..4716486 - 447 WP_277414633.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
PX653_RS20875 (PX653_20875) 4716607..4718478 - 1872 WP_277414634.1 potassium transporter Kup -
PX653_RS20880 (PX653_20880) 4718692..4719573 + 882 WP_277414635.1 EamA family transporter RarD -
PX653_RS20885 (PX653_20885) 4719586..4720035 - 450 WP_277414636.1 type II toxin-antitoxin system VapC family toxin Toxin
PX653_RS20890 (PX653_20890) 4720042..4720248 - 207 WP_277418626.1 DNA-binding protein Antitoxin
PX653_RS20895 (PX653_20895) 4720427..4722094 + 1668 WP_277414637.1 energy-dependent translational throttle protein EttA -
PX653_RS20900 (PX653_20900) 4722252..4722845 - 594 WP_277414638.1 outer membrane beta-barrel protein -
PX653_RS20905 (PX653_20905) 4723157..4723759 + 603 WP_277414639.1 hypothetical protein -
PX653_RS20910 (PX653_20910) 4723725..4724327 - 603 WP_277414640.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
PX653_RS20915 (PX653_20915) 4724367..4724945 + 579 WP_277414641.1 molybdopterin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 150 a.a.        Molecular weight: 16420.69 Da        Isoelectric Point: 5.2305

>T273744 WP_277414636.1 NZ_CP119083:c4720035-4719586 [Telluria chitinolytica]
MYLLDTNVISEYRKGARANRGVQAFFAEVQSEALFLPAQVIGEIQAGIARLRRQQDELAVQRAGMYERWLEELLDVFGAR
VLEFDTEAARVWGTLLGNDKHDPHTIDKQIAAIALVHDLVVVTRDGGTAFASLRPVRALDPFSASVAAG

Download         Length: 450 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7688.81 Da        Isoelectric Point: 7.0133

>AT273744 WP_277418626.1 NZ_CP119083:c4720248-4720042 [Telluria chitinolytica]
MAQLLVRDIDEAVVEALKRTAAGNGRSAEAEHREILRSSLTVRPKKRSFKEVLAAMPYFEDDALFDVR

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References