Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 834831..835488 Replicon chromosome
Accession NZ_CP119076
Organism Klebsiella aerogenes strain RX7.1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PYR66_RS04060 Protein ID WP_275048892.1
Coordinates 835078..835488 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag PYR66_RS04055 Protein ID WP_275048891.1
Coordinates 834831..835097 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR66_RS04030 (PYR66_04030) 829912..831345 - 1434 WP_275048888.1 6-phospho-beta-glucosidase BglA -
PYR66_RS04035 (PYR66_04035) 831465..832193 - 729 WP_275050238.1 MurR/RpiR family transcriptional regulator -
PYR66_RS04040 (PYR66_04040) 832244..832555 + 312 WP_275048889.1 N(4)-acetylcytidine aminohydrolase -
PYR66_RS04045 (PYR66_04045) 832719..833378 + 660 WP_008806429.1 hemolysin III family protein -
PYR66_RS04050 (PYR66_04050) 833613..834596 - 984 WP_275048890.1 tRNA-modifying protein YgfZ -
PYR66_RS04055 (PYR66_04055) 834831..835097 + 267 WP_275048891.1 FAD assembly factor SdhE Antitoxin
PYR66_RS04060 (PYR66_04060) 835078..835488 + 411 WP_275048892.1 protein YgfX Toxin
PYR66_RS04065 (PYR66_04065) 835496..836017 - 522 WP_275048893.1 flavodoxin FldB -
PYR66_RS04070 (PYR66_04070) 836118..837014 + 897 WP_275048894.1 site-specific tyrosine recombinase XerD -
PYR66_RS04075 (PYR66_04075) 837037..837750 + 714 WP_087859749.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PYR66_RS04080 (PYR66_04080) 837756..839489 + 1734 WP_275048895.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15866.61 Da        Isoelectric Point: 10.4436

>T273732 WP_275048892.1 NZ_CP119076:835078-835488 [Klebsiella aerogenes]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHACQGEIKLLIDSRLRWQKT
EWDIVGTPWVISSGMLLRLKQAESGRSQHLWVAADSMDAGEWRDLRRLVQQKPARD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10565.06 Da        Isoelectric Point: 5.6963

>AT273732 WP_275048891.1 NZ_CP119076:834831-835097 [Klebsiella aerogenes]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGKPADAQLQRMVNLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References