Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2044423..2044568 | Replicon | chromosome |
| Accession | NZ_CP119013 | ||
| Organism | Klebsiella pneumoniae strain CR-hvKP005 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2044459..2044561 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2044423..2044568 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PY729_RS10005 (PY729_10005) | 2039553..2041613 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| PY729_RS10010 (PY729_10010) | 2041617..2042276 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| PY729_RS10015 (PY729_10015) | 2042355..2042585 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| PY729_RS10020 (PY729_10020) | 2042698..2043072 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| PY729_RS10025 (PY729_10025) | 2043076..2043945 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| PY729_RS10030 (PY729_10030) | 2043962..2044300 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2044423..2044568 | - | 146 | - | - | Antitoxin |
| - | 2044459..2044561 | + | 103 | - | - | Toxin |
| PY729_RS10035 (PY729_10035) | 2044936..2045079 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| PY729_RS10040 (PY729_10040) | 2045184..2046152 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| PY729_RS10045 (PY729_10045) | 2046309..2046962 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| PY729_RS10050 (PY729_10050) | 2046959..2047150 | - | 192 | WP_002911395.1 | YebW family protein | - |
| PY729_RS10055 (PY729_10055) | 2047248..2047487 | - | 240 | WP_002911393.1 | YebV family protein | - |
| PY729_RS10060 (PY729_10060) | 2047603..2049036 | - | 1434 | WP_101345779.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T273710 NZ_CP119013:2044459-2044561 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT273710 NZ_CP119013:c2044568-2044423 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
