Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 919598..920348 Replicon chromosome
Accession NZ_CP118974
Organism Mammaliicoccus vitulinus strain DSM 15615

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYW35_RS04670 Protein ID WP_233709559.1
Coordinates 920202..920348 (+) Length 49 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYW35_RS04665 Protein ID WP_016913145.1
Coordinates 919598..920197 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYW35_RS04640 915457..916218 + 762 WP_103323121.1 acetylglutamate kinase -
PYW35_RS04645 916541..917668 + 1128 WP_016913149.1 tRNA epoxyqueuosine(34) reductase QueG -
PYW35_RS04650 917672..918145 + 474 WP_103323120.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PYW35_RS04655 918175..918312 - 138 WP_016913147.1 hypothetical protein -
PYW35_RS04660 918399..919550 + 1152 WP_103323119.1 N-acetylglucosamine-6-phosphate deacetylase -
PYW35_RS04665 919598..920197 + 600 WP_016913145.1 hypothetical protein Antitoxin
PYW35_RS04670 920202..920348 + 147 WP_233709559.1 SAS053 family protein Toxin
PYW35_RS04675 921193..922581 + 1389 WP_103323118.1 class II fumarate hydratase -
PYW35_RS04680 922670..924196 + 1527 WP_103323117.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 49 a.a.        Molecular weight: 5721.14 Da        Isoelectric Point: 3.8810

>T273682 WP_233709559.1 NZ_CP118974:920202-920348 [Mammaliicoccus vitulinus]
VKLLNKHPEEENEMVQDLDDVKELGKEMEQISEQNDEAYEEKKEEQDS

Download         Length: 147 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22350.23 Da        Isoelectric Point: 4.9814

>AT273682 WP_016913145.1 NZ_CP118974:919598-920197 [Mammaliicoccus vitulinus]
MALNFKVFETKDIAARYAADVVRKQFNSDSTSVVGIHLDAENTSFFDELLDDVKKNPVNFSQIHVLDFDGKEDYYTELGV
PKKQVLKTDVGSDVESFIKDKVNTDKKKNKLMLDVITLTEDSRTGLDYNQAIHPAREVIVLVTGKEKAKAVSQLYEEPAN
GSVESAKLKQHRMVTVLLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References