Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071202..2071473 Replicon chromosome
Accession NC_017635
Organism Escherichia coli W

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071240..2071343 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071202..2071473 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECW_RS10305 2068359..2069798 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECW_RS10310 2069916..2070152 + 237 WP_001295499.1 DUF1480 family protein -
ECW_RS10315 2070257..2070448 + 192 WP_001296140.1 YebW family protein -
ECW_RS10320 2070449..2071105 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2071202..2071473 + 272 - - Antitoxin
- 2071240..2071343 - 104 - - Toxin
ECW_RS10330 2071501..2071842 - 342 WP_000976472.1 YebY family protein -
ECW_RS10335 2071855..2072727 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
ECW_RS10340 2072731..2073105 - 375 WP_000204699.1 CopC domain-containing protein YobA -
ECW_RS10345 2073244..2073474 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECW_RS10350 2073576..2074232 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECW_RS10355 2074256..2074918 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T27367 NC_017635:c2071343-2071240 [Escherichia coli W]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT27367 NC_017635:2071202-2071473 [Escherichia coli W]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References