Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 488541..489177 Replicon chromosome
Accession NZ_CP118963
Organism Acinetobacter lwoffii strain DSM 2403

Toxin (Protein)


Gene name cptA Uniprot ID N8Q3V1
Locus tag PYW33_RS02215 Protein ID WP_004645066.1
Coordinates 488791..489177 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N8Q7K6
Locus tag PYW33_RS02210 Protein ID WP_004645065.1
Coordinates 488541..488798 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYW33_RS02190 484022..485029 + 1008 WP_004281489.1 DNA-directed RNA polymerase subunit alpha -
PYW33_RS02195 485048..485413 + 366 WP_004281488.1 50S ribosomal protein L17 -
PYW33_RS02200 485634..487124 + 1491 WP_004645062.1 NAD(P)/FAD-dependent oxidoreductase -
PYW33_RS02205 487185..488357 - 1173 WP_004645063.1 acyl-CoA dehydrogenase family protein -
PYW33_RS02210 488541..488798 + 258 WP_004645065.1 succinate dehydrogenase assembly factor 2 Antitoxin
PYW33_RS02215 488791..489177 + 387 WP_004645066.1 hypothetical protein Toxin
PYW33_RS02220 489713..490753 + 1041 WP_004645068.1 hypothetical protein -
PYW33_RS02225 490821..491393 + 573 WP_004281478.1 rhombosortase -
PYW33_RS02230 491591..493873 + 2283 WP_004645069.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-80)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15313.44 Da        Isoelectric Point: 10.1100

>T273668 WP_004645066.1 NZ_CP118963:488791-489177 [Acinetobacter lwoffii]
MDNRCFKLKRSLCALAFQLFIFALLMYLLYQLLPIAIWAVCVVIGLVIYQLFYRKTPQIEQFEYLDGREWSLTTKARPTR
RVFISHVIDHQAYIVVYFQHAKARPLLIWCDQLPFKQWKSLKVLTKLV

Download         Length: 387 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10366.85 Da        Isoelectric Point: 4.4809

>AT273668 WP_004645065.1 NZ_CP118963:488541-488798 [Acinetobacter lwoffii]
MTDDISLEERKVIYRARRGLKELDVYFDPYVKNYYLNAEPFEKQMFAELVEQEDPDLLDWFMEVSEPPRPELKDFIKKLK
FYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB N8Q3V1

Antitoxin

Source ID Structure
AlphaFold DB N8Q7K6

References