Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) tsbAT/-
Location 895746..896527 Replicon chromosome
Accession NZ_CP118953
Organism Staphylococcus chromogenes strain DSM 20454

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYW36_RS04370 Protein ID WP_157946077.1
Coordinates 896363..896527 (+) Length 55 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYW36_RS04365 Protein ID WP_037577237.1
Coordinates 895746..896345 (+) Length 200 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYW36_RS04345 891930..892652 + 723 WP_037577247.1 amino acid ABC transporter ATP-binding protein -
PYW36_RS04350 892940..894073 + 1134 WP_037577244.1 tRNA epoxyqueuosine(34) reductase QueG -
PYW36_RS04355 894070..894540 + 471 WP_037577242.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PYW36_RS04360 894558..895727 + 1170 WP_103159618.1 N-acetylglucosamine-6-phosphate deacetylase -
PYW36_RS04365 895746..896345 + 600 WP_037577237.1 glucosamine-6-phosphate isomerase Antitoxin
PYW36_RS04370 896363..896527 + 165 WP_157946077.1 SAS053 family protein Toxin
PYW36_RS04375 896627..897037 + 411 WP_103159619.1 hypothetical protein -
PYW36_RS04380 897182..898567 + 1386 WP_037577233.1 class II fumarate hydratase -
PYW36_RS04385 898589..900115 + 1527 WP_103159620.1 exopolyphosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(135-197)


Sequences


Toxin        


Download         Length: 55 a.a.        Molecular weight: 6336.67 Da        Isoelectric Point: 3.8825

>T273635 WP_157946077.1 NZ_CP118953:896363-896527 [Staphylococcus chromogenes]
MTEEKHIEHENEMVDDFDDLVSLGKEMEQISEANDEEKENQTHDASIRSDKTEE

Download         Length: 165 bp


Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22353.29 Da        Isoelectric Point: 6.1496

>AT273635 WP_037577237.1 NZ_CP118953:895746-896345 [Staphylococcus chromogenes]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLSGEEAPVLDYLKRNVDNHAVDFSQIHVLDYDKQTSYFKALGV
PEKQIHEIPEDDDVEKFIEHKAKTKDNKGKLTLQVVSINQNGEFGVPVNNGLKPAREIFVIVTGHDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPADVREYFTSLYA

Download         Length: 600 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References