Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 895746..896527 Replicon chromosome
Accession NZ_CP118953
Organism Staphylococcus chromogenes strain DSM 20454

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYW36_RS04370 Protein ID WP_157946077.1
Coordinates 896363..896527 (+) Length 55 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYW36_RS04365 Protein ID WP_037577237.1
Coordinates 895746..896345 (+) Length 200 a.a.

Genomic Context

PYW36_RS04345PYW36_RS04350PYW36_RS04355PYW36_RS04360PYW36_RS04365PYW36_RS04370PYW36_RS04375PYW36_RS04380PYW36_RS04385
Location: 891930..892652 (723 bp)
Type: Others
Protein ID: WP_037577247.1
Location: 892940..894073 (1134 bp)
Type: Others
Protein ID: WP_037577244.1
Location: 894070..894540 (471 bp)
Type: Others
Protein ID: WP_037577242.1
Location: 894558..895727 (1170 bp)
Type: Others
Protein ID: WP_103159618.1
Location: 895746..896345 (600 bp)
Type: Antitoxin
Protein ID: WP_037577237.1
Location: 896363..896527 (165 bp)
Type: Toxin
Protein ID: WP_157946077.1
Location: 896627..897037 (411 bp)
Type: Others
Protein ID: WP_103159619.1
Location: 897182..898567 (1386 bp)
Type: Others
Protein ID: WP_037577233.1
Location: 898589..900115 (1527 bp)
Type: Others
Protein ID: WP_103159620.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PYW36_RS04345891930..892652+723WP_037577247.1amino acid ABC transporter ATP-binding protein-
PYW36_RS04350892940..894073+1134WP_037577244.1tRNA epoxyqueuosine(34) reductase QueG-
PYW36_RS04355894070..894540+471WP_037577242.1tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL-
PYW36_RS04360894558..895727+1170WP_103159618.1N-acetylglucosamine-6-phosphate deacetylase-
PYW36_RS04365895746..896345+600WP_037577237.1glucosamine-6-phosphate isomeraseAntitoxin
PYW36_RS04370896363..896527+165WP_157946077.1SAS053 family proteinToxin
PYW36_RS04375896627..897037+411WP_103159619.1hypothetical protein-
PYW36_RS04380897182..898567+1386WP_037577233.1class II fumarate hydratase-
PYW36_RS04385898589..900115+1527WP_103159620.1exopolyphosphatase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(135-197)


Sequences

Toxin        


Download         Length: 55 a.a.        Molecular weight: 6336.67 Da        Isoelectric Point: 3.8825

>T273635 WP_157946077.1 NZ_CP118953:896363-896527 [Staphylococcus chromogenes]
MTEEKHIEHENEMVDDFDDLVSLGKEMEQISEANDEEKENQTHDASIRSDKTEE

Download         Length: 165 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22353.29 Da        Isoelectric Point: 6.1496

>AT273635 WP_037577237.1 NZ_CP118953:895746-896345 [Staphylococcus chromogenes]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLSGEEAPVLDYLKRNVDNHAVDFSQIHVLDYDKQTSYFKALGV
PEKQIHEIPEDDDVEKFIEHKAKTKDNKGKLTLQVVSINQNGEFGVPVNNGLKPAREIFVIVTGHDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPADVREYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References