Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 9846..10402 Replicon plasmid pK533-strA
Accession NZ_CP118944
Organism Aeromonas hydrophila strain K533

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PY771_RS25115 Protein ID WP_182936448.1
Coordinates 9846..10121 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PY771_RS25120 Protein ID WP_182936447.1
Coordinates 10121..10402 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY771_RS25090 (PY771_25090) 5886..6092 - 207 Protein_5 transposase -
PY771_RS25095 (PY771_25095) 6079..6246 + 168 Protein_6 IS5/IS1182 family transposase -
PY771_RS25100 (PY771_25100) 6492..7607 + 1116 WP_275116042.1 hypothetical protein -
PY771_RS25105 (PY771_25105) 8023..8532 - 510 WP_275116043.1 hypothetical protein -
PY771_RS25110 (PY771_25110) 9068..9796 - 729 WP_182936449.1 carbonic anhydrase -
PY771_RS25115 (PY771_25115) 9846..10121 - 276 WP_182936448.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PY771_RS25120 (PY771_25120) 10121..10402 - 282 WP_182936447.1 ribbon-helix-helix domain-containing protein Antitoxin
PY771_RS25125 (PY771_25125) 10614..11171 + 558 WP_048607679.1 recombinase family protein -
PY771_RS25130 (PY771_25130) 11174..14155 + 2982 WP_275116044.1 Tn3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid aph(3'')-Ib / aph(6)-Id - 1..100830 100830
- inside IScluster/Tn aph(3'')-Ib / aph(6)-Id - 3303..45627 42324


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(13-50)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10676.43 Da        Isoelectric Point: 9.5291

>T273631 WP_182936448.1 NZ_CP118944:c10121-9846 [Aeromonas hydrophila]
MELKWTSKALSDLTRLYEFLALANKPAAARVVQALTQAPAILLTNPRIGEQLFQFEPREVRRMLVGEYEVRYELLDSSIY
ILRLWHTREAR

Download         Length: 276 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10368.83 Da        Isoelectric Point: 5.6706

>AT273631 WP_182936447.1 NZ_CP118944:c10402-10121 [Aeromonas hydrophila]
MKSNMTQATTKVLTAHVPLPMADKVDQMAARLERSRGWIMKQALSAWIAQEEDRDRLTQEALADVEAGRVIDHLAVQAWA
DSLSTDQPLSVPR

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References