Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 2787080..2788644 | Replicon | chromosome |
Accession | NZ_CP118939 | ||
Organism | Aeromonas caviae strain K524 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | A0A2L0TXX7 |
Locus tag | PY772_RS13060 | Protein ID | WP_059169586.1 |
Coordinates | 2787334..2788644 (+) | Length | 437 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | PY772_RS13055 | Protein ID | WP_005329233.1 |
Coordinates | 2787080..2787334 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PY772_RS13030 (PY772_13030) | 2782655..2783233 | - | 579 | WP_021140685.1 | hypothetical protein | - |
PY772_RS13035 (PY772_13035) | 2783565..2784017 | - | 453 | WP_021140686.1 | DUF2384 domain-containing protein | - |
PY772_RS13040 (PY772_13040) | 2784272..2785579 | + | 1308 | WP_270825577.1 | Fic family protein | - |
PY772_RS13045 (PY772_13045) | 2785658..2785909 | + | 252 | WP_010674977.1 | plasmid stabilization protein | - |
PY772_RS13050 (PY772_13050) | 2786330..2786578 | - | 249 | WP_160839436.1 | hypothetical protein | - |
PY772_RS13055 (PY772_13055) | 2787080..2787334 | + | 255 | WP_005329233.1 | helix-turn-helix domain-containing protein | Antitoxin |
PY772_RS13060 (PY772_13060) | 2787334..2788644 | + | 1311 | WP_059169586.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
PY772_RS13070 (PY772_13070) | 2789501..2790532 | + | 1032 | WP_114523370.1 | IS630-like element ISAhy2 family transposase | - |
PY772_RS13080 (PY772_13080) | 2792474..2793064 | + | 591 | WP_223917505.1 | restriction endonuclease subunit S | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 437 a.a. Molecular weight: 49136.32 Da Isoelectric Point: 7.1717
>T273620 WP_059169586.1 NZ_CP118939:2787334-2788644 [Aeromonas caviae]
MASLTVYMNGYRVGTFTKATNGAHQFQYDESWVKLPGSRPISLSMPLRQQRYQGDEAYNFFDNLLPDNPEVRNRVVARYQ
ADSTQPFDLLSCIGQDSVGALQLVAQGRPVPDVKRIECKPLSDAELEQILTSYQQGIPLGMVREEDDFRISIAGAQEKTA
LLYLDNRWCLPHAATPTTHIIKLPIGKIESHSYSIDLSQSVENEYLCTLIAKALGLPVPHCFIMQVGKVKALAVERFDRR
YATDRSWIMRLPQEDFCQVLNVPSARKYESHGGPGIADIMTTLLGSATPEQDRYLFMKSQVLFWLLAATDGHAKNFSVFI
EPEGRFRLTPFYDILSMYPAFGGKGLHPRDAKLAMGLTATKGKKYAIEQIFPRHFYQTAKTIGFEQVQMEKIISELTDNL
DEVISIVRQQLPDTFPTEIADSILGGLSSRAQRLKR
MASLTVYMNGYRVGTFTKATNGAHQFQYDESWVKLPGSRPISLSMPLRQQRYQGDEAYNFFDNLLPDNPEVRNRVVARYQ
ADSTQPFDLLSCIGQDSVGALQLVAQGRPVPDVKRIECKPLSDAELEQILTSYQQGIPLGMVREEDDFRISIAGAQEKTA
LLYLDNRWCLPHAATPTTHIIKLPIGKIESHSYSIDLSQSVENEYLCTLIAKALGLPVPHCFIMQVGKVKALAVERFDRR
YATDRSWIMRLPQEDFCQVLNVPSARKYESHGGPGIADIMTTLLGSATPEQDRYLFMKSQVLFWLLAATDGHAKNFSVFI
EPEGRFRLTPFYDILSMYPAFGGKGLHPRDAKLAMGLTATKGKKYAIEQIFPRHFYQTAKTIGFEQVQMEKIISELTDNL
DEVISIVRQQLPDTFPTEIADSILGGLSSRAQRLKR
Download Length: 1311 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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