Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4135837..4136506 Replicon chromosome
Accession NZ_CP118932
Organism Serratia marcescens strain RX11

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PXW05_RS19800 Protein ID WP_265261371.1
Coordinates 4135837..4136259 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag PXW05_RS19805 Protein ID WP_004931679.1
Coordinates 4136240..4136506 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXW05_RS19780 (PXW05_19780) 4131766..4133499 - 1734 WP_004931690.1 single-stranded-DNA-specific exonuclease RecJ -
PXW05_RS19785 (PXW05_19785) 4133506..4134222 - 717 WP_004931688.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PXW05_RS19790 (PXW05_19790) 4134249..4135148 - 900 WP_048795302.1 site-specific tyrosine recombinase XerD -
PXW05_RS19795 (PXW05_19795) 4135255..4135773 + 519 WP_004931683.1 flavodoxin FldB -
PXW05_RS19800 (PXW05_19800) 4135837..4136259 - 423 WP_265261371.1 protein YgfX Toxin
PXW05_RS19805 (PXW05_19805) 4136240..4136506 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
PXW05_RS19810 (PXW05_19810) 4136827..4137819 + 993 WP_265261370.1 tRNA-modifying protein YgfZ -
PXW05_RS19815 (PXW05_19815) 4137858..4138355 - 498 WP_004931675.1 DUF2165 domain-containing protein -
PXW05_RS19820 (PXW05_19820) 4138506..4139180 - 675 WP_021505704.1 hemolysin III family protein -
PXW05_RS19825 (PXW05_19825) 4139364..4139972 + 609 WP_004931670.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16519.59 Da        Isoelectric Point: 10.9963

>T273601 WP_265261371.1 NZ_CP118932:c4136259-4135837 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGDGEQD

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT273601 WP_004931679.1 NZ_CP118932:c4136506-4136240 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References