Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 176656..177128 Replicon chromosome
Accession NZ_CP118932
Organism Serratia marcescens strain RX11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PXW05_RS00805 Protein ID WP_049186130.1
Coordinates 176853..177128 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PXW05_RS00800 Protein ID WP_049186131.1
Coordinates 176656..176853 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXW05_RS00770 (PXW05_00770) 171851..173119 + 1269 WP_275095957.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
PXW05_RS00775 (PXW05_00775) 173116..174315 + 1200 WP_275095328.1 anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC -
PXW05_RS00780 (PXW05_00780) 174350..174913 - 564 WP_004934304.1 DcrB family lipoprotein -
PXW05_RS00785 (PXW05_00785) 174994..175428 - 435 WP_004934307.1 GNAT family N-acetyltransferase -
PXW05_RS00790 (PXW05_00790) 175470..176129 - 660 WP_004934310.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
PXW05_RS00795 (PXW05_00795) 176350..176595 + 246 WP_004934314.1 sulfurtransferase TusA -
PXW05_RS00800 (PXW05_00800) 176656..176853 + 198 WP_049186131.1 hypothetical protein Antitoxin
PXW05_RS00805 (PXW05_00805) 176853..177128 + 276 WP_049186130.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PXW05_RS00810 (PXW05_00810) 177188..179506 - 2319 WP_049186128.1 zinc/cadmium/mercury/lead-transporting ATPase -
PXW05_RS00815 (PXW05_00815) 180189..181652 + 1464 WP_004934318.1 serralysin family metalloprotease -
PXW05_RS00820 (PXW05_00820) 181708..182085 + 378 WP_004934320.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10697.67 Da        Isoelectric Point: 11.5760

>T273592 WP_049186130.1 NZ_CP118932:176853-177128 [Serratia marcescens]
MLNIEWTRAARRDLVEIVGFIANDNPLAARKMKLLIMEAVIPAARHPRLFRRGRVDGTHEIPLHPNYLLVYQVLETHIRV
LRVLHARRQYP

Download         Length: 276 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7297.33 Da        Isoelectric Point: 4.1503

>AT273592 WP_049186131.1 NZ_CP118932:176656-176853 [Serratia marcescens]
MSILLLPTVAKMENEEHTQGYERWFLESVQEAMDEPLPGIPHDEVMAEMDAVIAAAEARIKAKQS

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References