Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3705500..3706206 Replicon chromosome
Accession NZ_CP118927
Organism Citrobacter koseri strain L2395

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag PX343_RS17720 Protein ID WP_121265183.1
Coordinates 3705500..3705868 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PX343_RS17725 Protein ID WP_275055238.1
Coordinates 3705889..3706206 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PX343_RS17700 (PX343_17700) 3701232..3701714 + 483 WP_012133757.1 L-2-amino-thiazoline-4-carboxylic acid hydrolase -
PX343_RS17705 (PX343_17705) 3701711..3702934 + 1224 WP_275055236.1 Zn-dependent hydrolase -
PX343_RS17710 (PX343_17710) 3703204..3704187 + 984 WP_275055237.1 DUF1852 domain-containing protein -
PX343_RS17715 (PX343_17715) 3704215..3705246 + 1032 WP_115615052.1 methionine synthase -
PX343_RS17720 (PX343_17720) 3705500..3705868 - 369 WP_121265183.1 TA system toxin CbtA family protein Toxin
PX343_RS17725 (PX343_17725) 3705889..3706206 - 318 WP_275055238.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PX343_RS17730 (PX343_17730) 3706225..3706446 - 222 WP_023233115.1 DUF987 domain-containing protein -
PX343_RS17735 (PX343_17735) 3706455..3706931 - 477 WP_114263041.1 RadC family protein -
PX343_RS17740 (PX343_17740) 3706947..3707411 - 465 WP_121265179.1 antirestriction protein -
PX343_RS17745 (PX343_17745) 3707553..3710396 - 2844 WP_275055239.1 Ag43/Cah family autotransporter adhesin -
PX343_RS17750 (PX343_17750) 3710469..3711155 - 687 WP_275055240.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3704215..3731451 27236


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13743.06 Da        Isoelectric Point: 9.1662

>T273579 WP_121265183.1 NZ_CP118927:c3705868-3705500 [Citrobacter koseri]
MKKLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQIQAPYLTTTDILQARKACGLMSRCSYREVSNIVLSRSRL

Download         Length: 369 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11836.57 Da        Isoelectric Point: 8.1483

>AT273579 WP_275055238.1 NZ_CP118927:c3706206-3705889 [Citrobacter koseri]
MSNITWGLQRNITPRLGARLVQEGNRLHYLADRASITGKFSKAECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References