Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1909611..1909756 Replicon chromosome
Accession NZ_CP118906
Organism Klebsiella pneumoniae strain T-hvKP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1909647..1909749 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1909611..1909756 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXG78_RS09145 1904741..1906801 + 2061 WP_004151449.1 oligopeptidase B -
PXG78_RS09150 1906805..1907464 - 660 WP_002911407.1 exodeoxyribonuclease X -
PXG78_RS09155 1907543..1907773 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PXG78_RS09160 1907886..1908260 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PXG78_RS09165 1908264..1909133 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
PXG78_RS09170 1909150..1909488 + 339 WP_002911404.1 YebY family protein -
- 1909611..1909756 - 146 - - Antitoxin
- 1909647..1909749 + 103 - - Toxin
PXG78_RS09175 1910124..1910267 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PXG78_RS09180 1910372..1911340 - 969 WP_014907334.1 VirK/YbjX family protein -
PXG78_RS09185 1911497..1912150 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
PXG78_RS09190 1912147..1912338 - 192 WP_002911395.1 YebW family protein -
PXG78_RS09195 1912436..1912675 - 240 WP_002911393.1 YebV family protein -
PXG78_RS09200 1912791..1914224 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273552 NZ_CP118906:1909647-1909749 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT273552 NZ_CP118906:c1909756-1909611 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References