Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1949117..1949262 Replicon chromosome
Accession NZ_CP118901
Organism Klebsiella pneumoniae strain CRKP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1949153..1949255 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1949117..1949262 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXG74_RS09340 1944247..1946307 + 2061 WP_047694778.1 oligopeptidase B -
PXG74_RS09345 1946311..1946970 - 660 WP_002911407.1 exodeoxyribonuclease X -
PXG74_RS09350 1947049..1947279 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PXG74_RS09355 1947392..1947766 + 375 WP_023285314.1 CopC domain-containing protein YobA -
PXG74_RS09360 1947770..1948639 + 870 WP_073553501.1 copper homeostasis membrane protein CopD -
PXG74_RS09365 1948656..1948994 + 339 WP_002911404.1 YebY family protein -
- 1949117..1949262 - 146 - - Antitoxin
- 1949153..1949255 + 103 - - Toxin
PXG74_RS09370 1949630..1949773 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PXG74_RS09375 1949878..1950846 - 969 WP_004151446.1 VirK/YbjX family protein -
PXG74_RS09380 1951003..1951656 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
PXG74_RS09385 1951653..1951844 - 192 WP_002911395.1 YebW family protein -
PXG74_RS09390 1951942..1952181 - 240 WP_002911393.1 YebV family protein -
PXG74_RS09395 1952297..1953730 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273534 NZ_CP118901:1949153-1949255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT273534 NZ_CP118901:c1949262-1949117 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References