273528

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 4537..5125 Replicon plasmid unnamed3
Accession NZ_CP118895
Organism Acinetobacter sp. TAC-1

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag PYV58_RS22785 Protein ID WP_275059842.1
Coordinates 4537..4824 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag PYV58_RS22790 Protein ID WP_275059843.1
Coordinates 4811..5125 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYV58_RS22760 (PYV58_22760) 1544..1927 + 384 WP_275059840.1 hypothetical protein -
PYV58_RS22765 (PYV58_22765) 2412..2609 - 198 WP_000476222.1 hypothetical protein -
PYV58_RS22770 (PYV58_22770) 2678..2905 - 228 WP_275059841.1 hypothetical protein -
PYV58_RS22775 (PYV58_22775) 3004..3219 - 216 WP_004637138.1 cold-shock protein -
PYV58_RS22780 (PYV58_22780) 3600..4136 - 537 WP_265755884.1 porin family protein -
PYV58_RS22785 (PYV58_22785) 4537..4824 + 288 WP_275059842.1 BrnT family toxin Toxin
PYV58_RS22790 (PYV58_22790) 4811..5125 + 315 WP_275059843.1 BrnA antitoxin family protein Antitoxin
PYV58_RS22795 (PYV58_22795) 5388..5804 - 417 Protein_8 hypothetical protein -
PYV58_RS22800 (PYV58_22800) 6002..6799 - 798 WP_086374408.1 protein phosphatase 2C domain-containing protein -
PYV58_RS22805 (PYV58_22805) 6861..7223 - 363 WP_275059837.1 hypothetical protein -
PYV58_RS22810 (PYV58_22810) 7289..7822 - 534 WP_180042157.1 hypothetical protein -
PYV58_RS22815 (PYV58_22815) 8020..8340 + 321 WP_180042155.1 type II toxin-antitoxin system RelE/ParE family toxin -
PYV58_RS22820 (PYV58_22820) 8333..8605 + 273 WP_180042153.1 NadS family protein -
PYV58_RS22825 (PYV58_22825) 9151..9540 + 390 Protein_14 hypothetical protein -
PYV58_RS22830 (PYV58_22830) 9592..9885 + 294 WP_227505690.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..11749 11749


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11223.59 Da        Isoelectric Point: 4.6327

>T273528 WP_275059842.1 NZ_CP118895:4537-4824 [Acinetobacter sp. TAC-1]
MELYFEWDEEKNQKNQKKHDVSFETASLIFDDPLRISIQDRHTGGEERWQTIGMVKGVLMLLVAHTIFDEDDCEIIRIIS
AREVTKAERNQYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12052.74 Da        Isoelectric Point: 9.7974

>AT273528 WP_275059843.1 NZ_CP118895:4811-5125 [Acinetobacter sp. TAC-1]
MSMVRYTRKELNKDFSDKQDAEIKSLLAKGTVPDDQLDLSDIPEITDWSNAVRHGQFYRPVKQQTSVRLDADVLSWLKAQ
GKGYQTRMNKILREAMLKDLKNHS

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References