273522

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 42648..43444 Replicon plasmid p12100-PER
Accession NZ_CP118865
Organism Providencia rettgeri strain 12100

Toxin (Protein)


Gene name TacT2 Uniprot ID A0A8I2DCD2
Locus tag NTP66_RS20630 Protein ID WP_042847109.1
Coordinates 42932..43444 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A8I2DCF1
Locus tag NTP66_RS20625 Protein ID WP_042847112.1
Coordinates 42648..42935 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTP66_RS20600 37906..38394 + 489 WP_042847123.1 hypothetical protein -
NTP66_RS20605 38429..38677 + 249 WP_282561982.1 hypothetical protein -
NTP66_RS20610 39294..39926 + 633 WP_052219367.1 hypothetical protein -
NTP66_RS20615 40206..41120 + 915 WP_042847118.1 tetratricopeptide repeat protein -
NTP66_RS20620 41216..42502 + 1287 WP_042847114.1 sel1 repeat family protein -
NTP66_RS20625 42648..42935 + 288 WP_042847112.1 DUF1778 domain-containing protein Antitoxin
NTP66_RS20630 42932..43444 + 513 WP_042847109.1 GNAT family N-acetyltransferase Toxin
NTP66_RS20635 43532..43813 + 282 WP_042847108.1 hypothetical protein -
NTP66_RS20640 43854..44243 + 390 WP_042847106.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid ant(3'')-Ia / qacE / sul1 / blaPER-1 / mph(A) / rmtB2 - 1..315510 315510


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(32-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18357.30 Da        Isoelectric Point: 9.5976

>T273522 WP_042847109.1 NZ_CP118865:42932-43444 [Providencia rettgeri]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKNRAMSNQNSGASRTFVTTSDNQVMGYYALSSGIVSTNQAVGRFRRNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGIVVHALTDDAKRFYEHIGFVPSPLDPMMLMITLAD
LQLAMGIHPN

Download         Length: 513 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10722.20 Da        Isoelectric Point: 8.6145

>AT273522 WP_042847112.1 NZ_CP118865:42648-42935 [Providencia rettgeri]
MATQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSPEVYQEFINQLDAAPRNN
EALRKTLMSKSPWEK

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References