Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2817217..2817752 Replicon chromosome
Accession NZ_CP118863
Organism Providencia rettgeri strain 12100

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NTP66_RS12540 Protein ID WP_140170723.1
Coordinates 2817444..2817752 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NTP66_RS12535 Protein ID WP_140170722.1
Coordinates 2817217..2817444 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTP66_RS12515 2812499..2812939 + 441 WP_110591516.1 flagellar export chaperone FlgN -
NTP66_RS12520 2813126..2813557 + 432 WP_140170720.1 hypothetical protein -
NTP66_RS12525 2813710..2815809 - 2100 WP_004255687.1 flagellar biosynthesis protein FlhA -
NTP66_RS12530 2815802..2816953 - 1152 WP_140170721.1 flagellar biosynthesis protein FlhB -
NTP66_RS12535 2817217..2817444 + 228 WP_140170722.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NTP66_RS12540 2817444..2817752 + 309 WP_140170723.1 CcdB family protein Toxin
NTP66_RS12545 2817768..2818325 + 558 WP_140170724.1 hypothetical protein -
NTP66_RS12550 2818368..2818574 - 207 WP_272661075.1 helix-turn-helix transcriptional regulator -
NTP66_RS12555 2818772..2819410 - 639 WP_094961165.1 protein phosphatase CheZ -
NTP66_RS12560 2819435..2819827 - 393 WP_004255705.1 chemotaxis response regulator CheY -
NTP66_RS12565 2819869..2820936 - 1068 WP_140170725.1 chemotaxis response regulator protein-glutamate methylesterase -
NTP66_RS12570 2820936..2821772 - 837 WP_004255713.1 chemotaxis protein-glutamate O-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(5-75)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11770.87 Da        Isoelectric Point: 8.0469

>T273516 WP_140170723.1 NZ_CP118863:2817444-2817752 [Providencia rettgeri]
MQYRLYQNRDDAIKYPYLLDIQSNIIDLLNTRLVIPLFDSRLVKKPLPARLNPQLVINGQVFILMTHQMACVPHSLLGKE
IVDLSSQRDTIKHAIDLLIDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8660.87 Da        Isoelectric Point: 8.9375

>AT273516 WP_140170722.1 NZ_CP118863:2817217-2817444 [Providencia rettgeri]
MNRTKKTVSVTVAPELYEQARRAKLNLSAILACALQAELKRLEAQKWKNDNAEGFNELNRINEEYGLLSDKYKDF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References