Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1484147..1484804 Replicon chromosome
Accession NZ_CP118863
Organism Providencia rettgeri strain 12100

Toxin (Protein)


Gene name cptA Uniprot ID A0A264VM08
Locus tag NTP66_RS06365 Protein ID WP_036958456.1
Coordinates 1484394..1484804 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4C097
Locus tag NTP66_RS06360 Protein ID WP_004261864.1
Coordinates 1484147..1484413 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTP66_RS06345 1481144..1482040 - 897 WP_180359477.1 hypothetical protein -
NTP66_RS06350 1482284..1482904 - 621 WP_200129308.1 HD domain-containing protein -
NTP66_RS06355 1482916..1483899 - 984 WP_140170983.1 tRNA-modifying protein YgfZ -
NTP66_RS06360 1484147..1484413 + 267 WP_004261864.1 FAD assembly factor SdhE Antitoxin
NTP66_RS06365 1484394..1484804 + 411 WP_036958456.1 protein YgfX Toxin
NTP66_RS06370 1484915..1485433 - 519 WP_140170981.1 flavodoxin FldB -
NTP66_RS06375 1485551..1486453 + 903 WP_004261814.1 site-specific tyrosine recombinase XerD -
NTP66_RS06380 1486475..1487179 + 705 WP_140170979.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NTP66_RS06385 1487189..1488922 + 1734 WP_140170977.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15568.53 Da        Isoelectric Point: 10.7733

>T273513 WP_036958456.1 NZ_CP118863:1484394-1484804 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLAPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKLHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10684.24 Da        Isoelectric Point: 4.8942

>AT273513 WP_004261864.1 NZ_CP118863:1484147-1484413 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDDLTTHDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A264VM08

Antitoxin

Source ID Structure
AlphaFold DB A0A345M2Q5

References