273512

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 883716..884254 Replicon chromosome
Accession NZ_CP118863
Organism Providencia rettgeri strain 12100

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NTP66_RS03770 Protein ID WP_140172124.1
Coordinates 883964..884254 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NTP66_RS03765 Protein ID WP_140172123.1
Coordinates 883716..883967 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTP66_RS03750 880129..881148 + 1020 WP_004905387.1 erythrose-4-phosphate dehydrogenase -
NTP66_RS03755 881241..882404 + 1164 WP_004905385.1 phosphoglycerate kinase -
NTP66_RS03760 882464..883540 + 1077 WP_094962157.1 class II fructose-bisphosphate aldolase -
NTP66_RS03765 883716..883967 + 252 WP_140172123.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NTP66_RS03770 883964..884254 + 291 WP_140172124.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NTP66_RS03775 884249..884605 - 357 WP_140172125.1 nuclear transport factor 2 family protein -
NTP66_RS03780 884602..885459 - 858 WP_180359520.1 LysR substrate-binding domain-containing protein -
NTP66_RS03785 885544..886230 + 687 WP_140172127.1 ankyrin repeat domain-containing protein -
NTP66_RS03790 886272..886697 + 426 WP_282555705.1 nucleoside deaminase -
NTP66_RS03795 886694..887875 + 1182 WP_096864804.1 cyanate transporter -
NTP66_RS03800 887972..888841 + 870 WP_140172129.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11124.23 Da        Isoelectric Point: 10.7261

>T273512 WP_140172124.1 NZ_CP118863:883964-884254 [Providencia rettgeri]
MTGFYKVKFRDDAAKEWKKLGATIQKQFAKKLKLLIENPHIPSARLSGLQNCYKIKLKASGYRLVYEVVDNQLIIIVVTV
GKRNRNEVYDIAKKRL

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9336.74 Da        Isoelectric Point: 4.2958

>AT273512 WP_140172123.1 NZ_CP118863:883716-883967 [Providencia rettgeri]
MPRVILSDVTASISELKKNPMATVDSGEGFPVAILNRNKPAFYCVPAEIYENLLEQIEDKELIEIVNARKNQKLVDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References