Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 912592..913342 Replicon chromosome
Accession NZ_CP118850
Organism Mammaliicoccus lentus strain 7047

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYH49_RS04695 Protein ID WP_282822161.1
Coordinates 913205..913342 (+) Length 46 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYH49_RS04690 Protein ID WP_282822159.1
Coordinates 912592..913191 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH49_RS04665 (PYH49_04665) 908609..909370 + 762 WP_016999955.1 acetylglutamate kinase -
PYH49_RS04670 (PYH49_04670) 909533..910660 + 1128 WP_147641105.1 tRNA epoxyqueuosine(34) reductase QueG -
PYH49_RS04675 (PYH49_04675) 910664..911137 + 474 WP_016999957.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PYH49_RS04680 (PYH49_04680) 911165..911305 - 141 WP_016999958.1 hypothetical protein -
PYH49_RS04685 (PYH49_04685) 911393..912547 + 1155 WP_103269526.1 N-acetylglucosamine-6-phosphate deacetylase -
PYH49_RS04690 (PYH49_04690) 912592..913191 + 600 WP_282822159.1 glucosamine-6-phosphate isomerase Antitoxin
PYH49_RS04695 (PYH49_04695) 913205..913342 + 138 WP_282822161.1 SAS053 family protein Toxin
PYH49_RS04700 (PYH49_04700) 913602..914990 + 1389 WP_282822163.1 class II fumarate hydratase -
PYH49_RS04705 (PYH49_04705) 915074..916600 + 1527 WP_103269529.1 Ppx/GppA family phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 5500.80 Da        Isoelectric Point: 3.7225

>T273507 WP_282822161.1 NZ_CP118850:913205-913342 [Mammaliicoccus lentus]
MDKHIDYNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEEK

Download         Length: 138 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22294.16 Da        Isoelectric Point: 5.1293

>AT273507 WP_282822159.1 NZ_CP118850:912592-913191 [Mammaliicoccus lentus]
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDDKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRTYFSIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References