Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1980194..1980944 Replicon chromosome
Accession NZ_CP118848
Organism Mammaliicoccus lentus strain 7048

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYH69_RS09925 Protein ID WP_016999961.1
Coordinates 1980194..1980331 (-) Length 46 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYH69_RS09930 Protein ID WP_103269527.1
Coordinates 1980345..1980944 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH69_RS09915 (PYH69_09915) 1976936..1978462 - 1527 WP_103269529.1 Ppx/GppA family phosphatase -
PYH69_RS09920 (PYH69_09920) 1978546..1979934 - 1389 WP_103269528.1 class II fumarate hydratase -
PYH69_RS09925 (PYH69_09925) 1980194..1980331 - 138 WP_016999961.1 SAS053 family protein Toxin
PYH69_RS09930 (PYH69_09930) 1980345..1980944 - 600 WP_103269527.1 glucosamine-6-phosphate isomerase Antitoxin
PYH69_RS09935 (PYH69_09935) 1980989..1982143 - 1155 WP_103269526.1 N-acetylglucosamine-6-phosphate deacetylase -
PYH69_RS09940 (PYH69_09940) 1982231..1982371 + 141 WP_016999958.1 hypothetical protein -
PYH69_RS09945 (PYH69_09945) 1982399..1982872 - 474 WP_016999957.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PYH69_RS09950 (PYH69_09950) 1982876..1984003 - 1128 WP_147641105.1 tRNA epoxyqueuosine(34) reductase QueG -
PYH69_RS09955 (PYH69_09955) 1984166..1984927 - 762 WP_016999955.1 acetylglutamate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 5474.76 Da        Isoelectric Point: 3.8145

>T273504 WP_016999961.1 NZ_CP118848:c1980331-1980194 [Mammaliicoccus lentus]
MDKHIDHNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEEK

Download         Length: 138 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22280.13 Da        Isoelectric Point: 5.1293

>AT273504 WP_103269527.1 NZ_CP118848:c1980944-1980345 [Mammaliicoccus lentus]
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDDKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References