Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1030324..1031129 Replicon chromosome
Accession NZ_CP118820
Organism Staphylococcus epidermidis strain 7057

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYH56_RS04980 Protein ID WP_002457885.1
Coordinates 1030947..1031129 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A0E1VBD1
Locus tag PYH56_RS04975 Protein ID WP_002446763.1
Coordinates 1030324..1030923 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1033909..1034220 311


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(125-195)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 7080.67 Da        Isoelectric Point: 4.3016

>T273449 WP_002457885.1 NZ_CP118820:1030947-1031129 [Staphylococcus epidermidis]
MANKKDSKLNYHEEENAMVTDLDDLKELGKEMEQISQENDEEKLNQPHDNEVRSDFKNSK

Download         Length: 183 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22635.54 Da        Isoelectric Point: 4.9942

>AT273449 WP_002446763.1 NZ_CP118820:1030324-1030923 [Staphylococcus epidermidis]
MAMNFKVFDNSEKVAEYTADILRKQFNNNPTTIAGFHLGKEHAPVFDELKKNVENHAVDFSQINILDYDDNHSYYEALGV
PTGQIYSISYENDAIDFISDKIKTKENKGKLTMQVLTIDENGKLDVSVRQGLMEAREIFLVITGANKRDMVEKLYRENGK
TSFEPSDLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0E1VBD1

References