Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) tsbAT/-
Location 909475..910225 Replicon chromosome
Accession NZ_CP118776
Organism Mammaliicoccus lentus strain 7074

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PYH61_RS04690 Protein ID WP_282822161.1
Coordinates 910088..910225 (+) Length 46 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag PYH61_RS04685 Protein ID WP_282822159.1
Coordinates 909475..910074 (+) Length 200 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH61_RS04660 (PYH61_04660) 905492..906253 + 762 WP_016999955.1 acetylglutamate kinase -
PYH61_RS04665 (PYH61_04665) 906416..907543 + 1128 WP_147641105.1 tRNA epoxyqueuosine(34) reductase QueG -
PYH61_RS04670 (PYH61_04670) 907547..908020 + 474 WP_016999957.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PYH61_RS04675 (PYH61_04675) 908048..908188 - 141 WP_016999958.1 hypothetical protein -
PYH61_RS04680 (PYH61_04680) 908276..909430 + 1155 WP_103269526.1 N-acetylglucosamine-6-phosphate deacetylase -
PYH61_RS04685 (PYH61_04685) 909475..910074 + 600 WP_282822159.1 glucosamine-6-phosphate isomerase Antitoxin
PYH61_RS04690 (PYH61_04690) 910088..910225 + 138 WP_282822161.1 SAS053 family protein Toxin
PYH61_RS04695 (PYH61_04695) 910485..911873 + 1389 WP_282822163.1 class II fumarate hydratase -
PYH61_RS04700 (PYH61_04700) 911957..913483 + 1527 WP_103269529.1 Ppx/GppA family phosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(134-195)


Sequences


Toxin        


Download         Length: 46 a.a.        Molecular weight: 5500.80 Da        Isoelectric Point: 3.7225

>T273440 WP_282822161.1 NZ_CP118776:910088-910225 [Mammaliicoccus lentus]
MDKHIDYNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEEK

Download         Length: 138 bp


Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22294.16 Da        Isoelectric Point: 5.1293

>AT273440 WP_282822159.1 NZ_CP118776:909475-910074 [Mammaliicoccus lentus]
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDDKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRTYFSIQFS

Download         Length: 600 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References