Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tsbAT/- |
Location | 909475..910225 | Replicon | chromosome |
Accession | NZ_CP118776 | ||
Organism | Mammaliicoccus lentus strain 7074 |
Toxin (Protein)
Gene name | tsbT | Uniprot ID | - |
Locus tag | PYH61_RS04690 | Protein ID | WP_282822161.1 |
Coordinates | 910088..910225 (+) | Length | 46 a.a. |
Antitoxin (Protein)
Gene name | tsbA | Uniprot ID | - |
Locus tag | PYH61_RS04685 | Protein ID | WP_282822159.1 |
Coordinates | 909475..910074 (+) | Length | 200 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PYH61_RS04660 (PYH61_04660) | 905492..906253 | + | 762 | WP_016999955.1 | acetylglutamate kinase | - |
PYH61_RS04665 (PYH61_04665) | 906416..907543 | + | 1128 | WP_147641105.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
PYH61_RS04670 (PYH61_04670) | 907547..908020 | + | 474 | WP_016999957.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
PYH61_RS04675 (PYH61_04675) | 908048..908188 | - | 141 | WP_016999958.1 | hypothetical protein | - |
PYH61_RS04680 (PYH61_04680) | 908276..909430 | + | 1155 | WP_103269526.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
PYH61_RS04685 (PYH61_04685) | 909475..910074 | + | 600 | WP_282822159.1 | glucosamine-6-phosphate isomerase | Antitoxin |
PYH61_RS04690 (PYH61_04690) | 910088..910225 | + | 138 | WP_282822161.1 | SAS053 family protein | Toxin |
PYH61_RS04695 (PYH61_04695) | 910485..911873 | + | 1389 | WP_282822163.1 | class II fumarate hydratase | - |
PYH61_RS04700 (PYH61_04700) | 911957..913483 | + | 1527 | WP_103269529.1 | Ppx/GppA family phosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 46 a.a. Molecular weight: 5500.80 Da Isoelectric Point: 3.7225
>T273440 WP_282822161.1 NZ_CP118776:910088-910225 [Mammaliicoccus lentus]
MDKHIDYNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEEK
MDKHIDYNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEEK
Download Length: 138 bp
Antitoxin
Download Length: 200 a.a. Molecular weight: 22294.16 Da Isoelectric Point: 5.1293
>AT273440 WP_282822159.1 NZ_CP118776:909475-910074 [Mammaliicoccus lentus]
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDDKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRTYFSIQFS
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDDKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRTYFSIQFS
Download Length: 600 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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