Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 6742634..6744090 Replicon chromosome
Accession NZ_CP118775
Organism Delftia tsuruhatensis strain ULwDis3

Toxin (Protein)


Gene name rlegT Uniprot ID A0A1D8J579
Locus tag PW274_RS31390 Protein ID WP_046239356.1
Coordinates 6743245..6744090 (+) Length 282 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag PW274_RS31385 Protein ID WP_016447321.1
Coordinates 6742634..6743248 (+) Length 205 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PW274_RS31370 (PW274_31370) 6738893..6740200 + 1308 WP_017405691.1 solute carrier family 23 protein -
PW274_RS31375 (PW274_31375) 6740408..6741922 + 1515 WP_012202025.1 acetyl-CoA hydrolase/transferase family protein -
PW274_RS31380 (PW274_31380) 6742053..6742526 + 474 WP_012202024.1 hotdog fold thioesterase -
PW274_RS31385 (PW274_31385) 6742634..6743248 + 615 WP_016447321.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
PW274_RS31390 (PW274_31390) 6743245..6744090 + 846 WP_046239356.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PW274_RS31395 (PW274_31395) 6744123..6744824 - 702 WP_017405695.1 ABC transporter ATP-binding protein -
PW274_RS31400 (PW274_31400) 6744829..6745587 - 759 WP_126311553.1 ABC transporter ATP-binding protein -
PW274_RS31405 (PW274_31405) 6745580..6746665 - 1086 WP_126311552.1 branched-chain amino acid ABC transporter permease -
PW274_RS31410 (PW274_31410) 6746669..6747541 - 873 WP_013799989.1 branched-chain amino acid ABC transporter permease -
PW274_RS31415 (PW274_31415) 6747592..6748755 - 1164 WP_126311551.1 ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 282 a.a.        Molecular weight: 31079.80 Da        Isoelectric Point: 8.1191

>T273438 WP_046239356.1 NZ_CP118775:6743245-6744090 [Delftia tsuruhatensis]
MSRDIAASIRARLKQCADARRQDFNLTLTHYGLERLLYRLSISPHADSYLLKGALLFAIWYEQPHRPTRDADLLGFGLDD
VDSAVSAFREICRIAVDDGIAFDAASVRGTAIRKEAGYGGVRIDLRATLDGARITLQVDIGFGDAVTPSPQAIRYPVLLD
GLPAPQLRSYPKYTVVAEKLHAICLLGMANTRMKDYFDLWVLMTEGTLDPAELRRAMKATFERRQLALPAGLPAGLSDGF
SSDAAKQAQWAAFLKKNRLEALELAPVVARLREEFQQCGIV

Download         Length: 846 bp


Antitoxin


Download         Length: 205 a.a.        Molecular weight: 21967.59 Da        Isoelectric Point: 9.9117

>AT273438 WP_016447321.1 NZ_CP118775:6742634-6743248 [Delftia tsuruhatensis]
MPAPGSALEQAVLALAEQRPLLRARDLAALGLPTMALSRLVAAGRLERVARGLYSLPGRPLSEHRSLAEVALRVPQGVVC
LLSALRVHGIGTQAPFEVWMAIPHHSPTPRIDQPALRAIRMSGAALSEGVETLQIDGVGVAVFNASKTVADCFKYRNKIG
LDVALEALRDGWAQRKLTADALWHYAAIDRVSNVMRPYLESIAA

Download         Length: 615 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A1D8J579


Antitoxin

Source ID Structure

References