273434

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2356757..2357799 Replicon chromosome
Accession NZ_CP118775
Organism Delftia tsuruhatensis strain ULwDis3

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag PW274_RS11065 Protein ID WP_003109777.1
Coordinates 2357224..2357799 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID I3TV68
Locus tag PW274_RS11060 Protein ID WP_003050245.1
Coordinates 2356757..2357227 (+) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PW274_RS11025 (PW274_11025) 2352149..2353567 - 1419 WP_003109776.1 TIGR03752 family integrating conjugative element protein -
PW274_RS11030 (PW274_11030) 2353557..2354468 - 912 WP_003105643.1 TIGR03749 family integrating conjugative element protein -
PW274_RS11035 (PW274_11035) 2354465..2355157 - 693 WP_003105641.1 TIGR03746 family integrating conjugative element protein -
PW274_RS11040 (PW274_11040) 2355154..2355552 - 399 WP_003105639.1 TIGR03750 family conjugal transfer protein -
PW274_RS11045 (PW274_11045) 2355564..2355923 - 360 WP_003090173.1 TIGR03745 family integrating conjugative element membrane protein -
PW274_RS11050 (PW274_11050) 2355940..2356173 - 234 WP_003050225.1 TIGR03758 family integrating conjugative element protein -
PW274_RS11055 (PW274_11055) 2356170..2356553 - 384 WP_003105635.1 RAQPRD family integrative conjugative element protein -
PW274_RS11060 (PW274_11060) 2356757..2357227 + 471 WP_003050245.1 helix-turn-helix domain-containing protein Antitoxin
PW274_RS11065 (PW274_11065) 2357224..2357799 + 576 WP_003109777.1 PIN domain-containing protein Toxin
PW274_RS11070 (PW274_11070) 2357817..2358731 + 915 WP_003105629.1 AAA family ATPase -
PW274_RS11075 (PW274_11075) 2358728..2359198 + 471 WP_003105626.1 type III CBASS phage resistance system CD-NTase-associated protein Cap8 -
PW274_RS11080 (PW274_11080) 2359195..2359695 + 501 WP_003090159.1 type III CBASS phage resistance system CD-NTase-associated protein Cap7 -
PW274_RS11085 (PW274_11085) 2359695..2360597 + 903 WP_003105624.1 CBASS oligonucleotide cyclase -
PW274_RS11090 (PW274_11090) 2360636..2361361 + 726 WP_003050273.1 CBASS effector endonuclease NucC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-114)

Antitoxin

Helix-turn-helix domain, group 17

(85-133)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21644.79 Da        Isoelectric Point: 5.6172

>T273434 WP_003109777.1 NZ_CP118775:2357224-2357799 [Delftia tsuruhatensis]
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPDDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIEVDRYLEILLRQGLVQTTKVLATYRTIL

Download         Length: 576 bp

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17245.62 Da        Isoelectric Point: 6.3803

>AT273434 WP_003050245.1 NZ_CP118775:2356757-2357227 [Delftia tsuruhatensis]
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE

Download         Length: 471 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I3TV68

References