Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
| Location | 4506532..4507331 | Replicon | chromosome |
| Accession | NZ_CP118774 | ||
| Organism | Citrobacter braakii strain ASE1 | ||
Toxin (Protein)
| Gene name | yjhX | Uniprot ID | A0A624XK42 |
| Locus tag | PXN04_RS21405 | Protein ID | WP_047643226.1 |
| Coordinates | 4507074..4507331 (-) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | yjhQ | Uniprot ID | A0A5Y9PB12 |
| Locus tag | PXN04_RS21400 | Protein ID | WP_072592468.1 |
| Coordinates | 4506532..4507062 (-) | Length | 177 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PXN04_RS21395 (PXN04_21395) | 4504036..4505832 | - | 1797 | WP_072592469.1 | POTRA domain-containing protein | - |
| PXN04_RS21400 (PXN04_21400) | 4506532..4507062 | - | 531 | WP_072592468.1 | N-acetyltransferase | Antitoxin |
| PXN04_RS21405 (PXN04_21405) | 4507074..4507331 | - | 258 | WP_047643226.1 | YjhX family toxin | Toxin |
| PXN04_RS21410 (PXN04_21410) | 4507631..4508008 | - | 378 | WP_000123000.1 | SH3 domain-containing protein | - |
| PXN04_RS21415 (PXN04_21415) | 4508021..4508715 | - | 695 | Protein_4192 | aspartate/glutamate racemase | - |
| PXN04_RS21420 (PXN04_21420) | 4509561..4509695 | + | 135 | WP_256862081.1 | hypothetical protein | - |
| PXN04_RS21425 (PXN04_21425) | 4509804..4510244 | + | 441 | WP_072592467.1 | methyl-accepting chemotaxis protein | - |
| PXN04_RS21430 (PXN04_21430) | 4510431..4510619 | + | 189 | WP_052032245.1 | methyl-accepting chemotaxis protein | - |
| PXN04_RS21435 (PXN04_21435) | 4510656..4510991 | + | 336 | WP_052032244.1 | hypothetical protein | - |
| PXN04_RS21440 (PXN04_21440) | 4511220..4511684 | + | 465 | WP_047643224.1 | DUF302 domain-containing protein | - |
| PXN04_RS21445 (PXN04_21445) | 4511746..4512012 | + | 267 | WP_023240809.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 4471827..4579247 | 107420 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9724.27 Da Isoelectric Point: 10.6133
>T273430 WP_047643226.1 NZ_CP118774:c4507331-4507074 [Citrobacter braakii]
MNLSRQEQRILHVLAKGGRIAHVRDASGRVTSVECYSREGLLLCDCTLEVFKKLRTKKLIKSVNGQPYRINTTELNNVRA
QLDNR
MNLSRQEQRILHVLAKGGRIAHVRDASGRVTSVECYSREGLLLCDCTLEVFKKLRTKKLIKSVNGQPYRINTTELNNVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 177 a.a. Molecular weight: 19377.37 Da Isoelectric Point: 6.7122
>AT273430 WP_072592468.1 NZ_CP118774:c4507062-4506532 [Citrobacter braakii]
MTAHHVTFHIADESDASDIREVETRAFGFSKEADLVASLLEDKSAHPALSLLARHEGKAVGHILFTRATFKGEMDSPLMQ
ILAPLAVIPEYQGMGMGGRLIRTGIEHLRLMGCQTVFVLGHVTYYPRHGFESCAGDKGYPAPYPIPEEHKTCWMMQLLTA
QPMKVTGHIQCAQACS
MTAHHVTFHIADESDASDIREVETRAFGFSKEADLVASLLEDKSAHPALSLLARHEGKAVGHILFTRATFKGEMDSPLMQ
ILAPLAVIPEYQGMGMGGRLIRTGIEHLRLMGCQTVFVLGHVTYYPRHGFESCAGDKGYPAPYPIPEEHKTCWMMQLLTA
QPMKVTGHIQCAQACS
Download Length: 531 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A624XK42 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A5Y9PB12 |