Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4049694..4050363 Replicon chromosome
Accession NZ_CP118723
Organism Serratia marcescens strain AHRB3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PWO23_RS19400 Protein ID WP_016929976.1
Coordinates 4049694..4050116 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag PWO23_RS19405 Protein ID WP_004931679.1
Coordinates 4050097..4050363 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWO23_RS19380 (PWO23_19390) 4045580..4046098 + 519 WP_004931683.1 flavodoxin FldB -
PWO23_RS19385 (PWO23_19395) 4046136..4047500 - 1365 WP_016929973.1 cell envelope integrity protein CreD -
PWO23_RS19390 (PWO23_19400) 4047581..4048999 - 1419 WP_016929974.1 two-component system sensor histidine kinase CreC -
PWO23_RS19395 (PWO23_19405) 4048996..4049694 - 699 WP_016929975.1 two-component system response regulator CreB -
PWO23_RS19400 (PWO23_19410) 4049694..4050116 - 423 WP_016929976.1 protein YgfX Toxin
PWO23_RS19405 (PWO23_19415) 4050097..4050363 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
PWO23_RS19410 (PWO23_19420) 4050684..4051676 + 993 WP_016929977.1 tRNA-modifying protein YgfZ -
PWO23_RS19415 (PWO23_19425) 4051715..4052212 - 498 WP_079452406.1 DUF2165 domain-containing protein -
PWO23_RS19420 (PWO23_19430) 4052363..4053037 - 675 WP_028127690.1 hemolysin III family protein -
PWO23_RS19425 (PWO23_19435) 4053221..4053829 + 609 WP_028127691.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T273393 WP_016929976.1 NZ_CP118723:c4050116-4049694 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT273393 WP_004931679.1 NZ_CP118723:c4050363-4050097 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References