Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929040..1929180 Replicon chromosome
Accession NZ_CP118723
Organism Serratia marcescens strain AHRB3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929084..1929180 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929040..1929180 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWO23_RS09250 (PWO23_09255) 1924307..1924702 + 396 WP_048322942.1 RidA family protein -
PWO23_RS09255 (PWO23_09260) 1924859..1925812 + 954 WP_004928848.1 prolyl aminopeptidase -
PWO23_RS09260 (PWO23_09265) 1925845..1926075 - 231 WP_016928156.1 DNA polymerase III subunit theta -
PWO23_RS09265 (PWO23_09270) 1926420..1926938 + 519 WP_274985369.1 non-heme ferritin -
PWO23_RS09270 (PWO23_09275) 1927231..1927647 + 417 WP_046686875.1 CopC domain-containing protein YobA -
PWO23_RS09275 (PWO23_09280) 1927650..1928531 + 882 WP_131164343.1 copper homeostasis membrane protein CopD -
PWO23_RS09280 (PWO23_09285) 1928601..1928942 + 342 WP_016928154.1 YebY family protein -
- 1929040..1929180 - 141 - - Antitoxin
- 1929084..1929180 + 97 - - Toxin
PWO23_RS09285 (PWO23_09290) 1929270..1929932 - 663 Protein_1785 tyrosine-type recombinase/integrase -
PWO23_RS09290 (PWO23_09295) 1931495..1931812 + 318 WP_274985370.1 phage holin family protein -
PWO23_RS09295 (PWO23_09300) 1931799..1932239 + 441 WP_274985371.1 lysozyme -
PWO23_RS09300 (PWO23_09305) 1932236..1932619 + 384 WP_274985372.1 hypothetical protein -
PWO23_RS09305 (PWO23_09310) 1932519..1932776 + 258 WP_274985373.1 Rz1-like lysis system protein LysC -
PWO23_RS09310 (PWO23_09315) 1932766..1932936 + 171 WP_154640827.1 hypothetical protein -
PWO23_RS09315 (PWO23_09320) 1932988..1933533 - 546 WP_274985374.1 hypothetical protein -
PWO23_RS09320 (PWO23_09325) 1933923..1934123 + 201 Protein_1792 glycoside hydrolase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T273387 NZ_CP118723:1929084-1929180 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT273387 NZ_CP118723:c1929180-1929040 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References