Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4077786..4078444 Replicon chromosome
Accession NZ_CP118713
Organism Rhizobium sp. BJ04

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PO860_RS19935 Protein ID WP_273884406.1
Coordinates 4078028..4078444 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PO860_RS19930 Protein ID WP_183608480.1
Coordinates 4077786..4078028 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO860_RS19905 (PO860_19905) 4073162..4074145 - 984 WP_273884409.1 UDP-glucose 4-epimerase GalE -
PO860_RS19910 (PO860_19910) 4074420..4075064 + 645 WP_272783520.1 ThuA domain-containing protein -
PO860_RS19915 (PO860_19915) 4075123..4075692 + 570 WP_273884408.1 GNAT family N-acetyltransferase -
PO860_RS19920 (PO860_19920) 4075727..4075978 - 252 WP_273881337.1 DUF2934 domain-containing protein -
PO860_RS19925 (PO860_19925) 4076180..4077616 + 1437 WP_273884407.1 hypothetical protein -
PO860_RS19930 (PO860_19930) 4077786..4078028 + 243 WP_183608480.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PO860_RS19935 (PO860_19935) 4078028..4078444 + 417 WP_273884406.1 type II toxin-antitoxin system VapC family toxin Toxin
PO860_RS19945 (PO860_19945) 4078919..4079236 + 318 WP_003543907.1 50S ribosomal protein L21 -
PO860_RS19950 (PO860_19950) 4079271..4079540 + 270 WP_003567620.1 50S ribosomal protein L27 -
PO860_RS19955 (PO860_19955) 4079666..4080322 + 657 WP_183608478.1 GNAT family protein -
PO860_RS19960 (PO860_19960) 4080319..4080906 + 588 WP_272783516.1 GNAT family N-acetyltransferase -
PO860_RS19965 (PO860_19965) 4080944..4081810 - 867 WP_272783515.1 endonuclease/exonuclease/phosphatase family protein -
PO860_RS19970 (PO860_19970) 4081895..4082977 + 1083 WP_273884404.1 GTPase ObgE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14940.95 Da        Isoelectric Point: 6.2307

>T273382 WP_273884406.1 NZ_CP118713:4078028-4078444 [Rhizobium sp. BJ04]
MIHLDTNVAVALLNGRPRQVRERFDEARNAGTPLGLSIIVYHELMYGAAASERRHANEEKIALFIASGGISLIDFNEGDA
QEAADIRAYLRRQGTPIGPYDVLIAAQARRAGTVLVTANTGEFVRVPGLQVLDWAAAS

Download         Length: 417 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8957.24 Da        Isoelectric Point: 7.0138

>AT273382 WP_183608480.1 NZ_CP118713:4077786-4078028 [Rhizobium sp. BJ04]
MSATAKLFTHGRSQAVRLPKEFRFEGKEVRVSRVGNRVILEPLDADNAMPWAAIDKLGDTPFMPEGREQPSMPADRAVFD

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References