Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4117492..4118150 Replicon chromosome
Accession NZ_CP118687
Organism Rhizobium sp. MJ22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PO862_RS20315 Protein ID WP_273884406.1
Coordinates 4117734..4118150 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PO862_RS20310 Protein ID WP_183608480.1
Coordinates 4117492..4117734 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO862_RS20285 (PO862_20285) 4112868..4113851 - 984 WP_275033022.1 UDP-glucose 4-epimerase GalE -
PO862_RS20290 (PO862_20290) 4114126..4114770 + 645 WP_272783520.1 ThuA domain-containing protein -
PO862_RS20295 (PO862_20295) 4114829..4115398 + 570 WP_275033025.1 GNAT family N-acetyltransferase -
PO862_RS20300 (PO862_20300) 4115433..4115684 - 252 WP_273881337.1 DUF2934 domain-containing protein -
PO862_RS20305 (PO862_20305) 4115886..4117322 + 1437 WP_273884407.1 hypothetical protein -
PO862_RS20310 (PO862_20310) 4117492..4117734 + 243 WP_183608480.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PO862_RS20315 (PO862_20315) 4117734..4118150 + 417 WP_273884406.1 type II toxin-antitoxin system VapC family toxin Toxin
PO862_RS20325 (PO862_20325) 4118625..4118942 + 318 WP_003543907.1 50S ribosomal protein L21 -
PO862_RS20330 (PO862_20330) 4118977..4119246 + 270 WP_003567620.1 50S ribosomal protein L27 -
PO862_RS20335 (PO862_20335) 4119372..4120028 + 657 WP_183608478.1 GNAT family protein -
PO862_RS20340 (PO862_20340) 4120025..4120612 + 588 WP_272783516.1 GNAT family N-acetyltransferase -
PO862_RS20345 (PO862_20345) 4120650..4121516 - 867 WP_272783515.1 endonuclease/exonuclease/phosphatase family protein -
PO862_RS20350 (PO862_20350) 4121601..4122683 + 1083 WP_273884404.1 GTPase ObgE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14940.95 Da        Isoelectric Point: 6.2307

>T273375 WP_273884406.1 NZ_CP118687:4117734-4118150 [Rhizobium sp. MJ22]
MIHLDTNVAVALLNGRPRQVRERFDEARNAGTPLGLSIIVYHELMYGAAASERRHANEEKIALFIASGGISLIDFNEGDA
QEAADIRAYLRRQGTPIGPYDVLIAAQARRAGTVLVTANTGEFVRVPGLQVLDWAAAS

Download         Length: 417 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8957.24 Da        Isoelectric Point: 7.0138

>AT273375 WP_183608480.1 NZ_CP118687:4117492-4117734 [Rhizobium sp. MJ22]
MSATAKLFTHGRSQAVRLPKEFRFEGKEVRVSRVGNRVILEPLDADNAMPWAAIDKLGDTPFMPEGREQPSMPADRAVFD

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References