Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4117492..4118150 Replicon chromosome
Accession NZ_CP118687
Organism Rhizobium sp. MJ22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PO862_RS20315 Protein ID WP_273884406.1
Coordinates 4117734..4118150 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PO862_RS20310 Protein ID WP_183608480.1
Coordinates 4117492..4117734 (+) Length 81 a.a.

Genomic Context

PO862_RS20290PO862_RS20295PO862_RS20305PO862_RS20310PO862_RS20315PO862_RS20325PO862_RS20330PO862_RS20335PO862_RS20340PO862_RS20350PO862_RS20285PO862_RS20300PO862_RS20345
Location: 4114126..4114770 (645 bp)
Type: Others
Protein ID: WP_272783520.1
Location: 4114829..4115398 (570 bp)
Type: Others
Protein ID: WP_275033025.1
Location: 4115886..4117322 (1437 bp)
Type: Others
Protein ID: WP_273884407.1
Location: 4117492..4117734 (243 bp)
Type: Antitoxin
Protein ID: WP_183608480.1
Location: 4117734..4118150 (417 bp)
Type: Toxin
Protein ID: WP_273884406.1
Location: 4118625..4118942 (318 bp)
Type: Others
Protein ID: WP_003543907.1
Location: 4118977..4119246 (270 bp)
Type: Others
Protein ID: WP_003567620.1
Location: 4119372..4120028 (657 bp)
Type: Others
Protein ID: WP_183608478.1
Location: 4120025..4120612 (588 bp)
Type: Others
Protein ID: WP_272783516.1
Location: 4121601..4122683 (1083 bp)
Type: Others
Protein ID: WP_273884404.1
Location: 4112868..4113851 (984 bp)
Type: Others
Protein ID: WP_275033022.1
Location: 4115433..4115684 (252 bp)
Type: Others
Protein ID: WP_273881337.1
Location: 4120650..4121516 (867 bp)
Type: Others
Protein ID: WP_272783515.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PO862_RS20285 (PO862_20285)4112868..4113851-984WP_275033022.1UDP-glucose 4-epimerase GalE-
PO862_RS20290 (PO862_20290)4114126..4114770+645WP_272783520.1ThuA domain-containing protein-
PO862_RS20295 (PO862_20295)4114829..4115398+570WP_275033025.1GNAT family N-acetyltransferase-
PO862_RS20300 (PO862_20300)4115433..4115684-252WP_273881337.1DUF2934 domain-containing protein-
PO862_RS20305 (PO862_20305)4115886..4117322+1437WP_273884407.1hypothetical protein-
PO862_RS20310 (PO862_20310)4117492..4117734+243WP_183608480.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
PO862_RS20315 (PO862_20315)4117734..4118150+417WP_273884406.1type II toxin-antitoxin system VapC family toxinToxin
PO862_RS20325 (PO862_20325)4118625..4118942+318WP_003543907.150S ribosomal protein L21-
PO862_RS20330 (PO862_20330)4118977..4119246+270WP_003567620.150S ribosomal protein L27-
PO862_RS20335 (PO862_20335)4119372..4120028+657WP_183608478.1GNAT family protein-
PO862_RS20340 (PO862_20340)4120025..4120612+588WP_272783516.1GNAT family N-acetyltransferase-
PO862_RS20345 (PO862_20345)4120650..4121516-867WP_272783515.1endonuclease/exonuclease/phosphatase family protein-
PO862_RS20350 (PO862_20350)4121601..4122683+1083WP_273884404.1GTPase ObgE-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14940.95 Da        Isoelectric Point: 6.2307

>T273375 WP_273884406.1 NZ_CP118687:4117734-4118150 [Rhizobium sp. MJ22]
MIHLDTNVAVALLNGRPRQVRERFDEARNAGTPLGLSIIVYHELMYGAAASERRHANEEKIALFIASGGISLIDFNEGDA
QEAADIRAYLRRQGTPIGPYDVLIAAQARRAGTVLVTANTGEFVRVPGLQVLDWAAAS

Download         Length: 417 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8957.24 Da        Isoelectric Point: 7.0138

>AT273375 WP_183608480.1 NZ_CP118687:4117492-4117734 [Rhizobium sp. MJ22]
MSATAKLFTHGRSQAVRLPKEFRFEGKEVRVSRVGNRVILEPLDADNAMPWAAIDKLGDTPFMPEGREQPSMPADRAVFD

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References