Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3957968..3958500 Replicon chromosome
Accession NZ_CP118687
Organism Rhizobium sp. MJ22

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PO862_RS19585 Protein ID WP_273884469.1
Coordinates 3957968..3958258 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PO862_RS19590 Protein ID WP_273881409.1
Coordinates 3958255..3958500 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO862_RS19565 (PO862_19565) 3953554..3954222 - 669 WP_273884473.1 NUDIX hydrolase -
PO862_RS19570 (PO862_19570) 3954393..3955295 + 903 WP_273884472.1 hypothetical protein -
PO862_RS19575 (PO862_19575) 3955353..3956582 + 1230 WP_275032846.1 adenylosuccinate synthetase -
PO862_RS19580 (PO862_19580) 3956638..3957861 - 1224 WP_183608611.1 argininosuccinate synthase -
PO862_RS19585 (PO862_19585) 3957968..3958258 - 291 WP_273884469.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO862_RS19590 (PO862_19590) 3958255..3958500 - 246 WP_273881409.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PO862_RS19595 (PO862_19595) 3958585..3959436 + 852 WP_183608609.1 SDR family NAD(P)-dependent oxidoreductase -
PO862_RS19600 (PO862_19600) 3959521..3960162 + 642 WP_183608608.1 LysE family translocator -
PO862_RS19605 (PO862_19605) 3960211..3961005 - 795 WP_171604563.1 ABC transporter ATP-binding protein -
PO862_RS19610 (PO862_19610) 3961002..3961880 - 879 WP_273881407.1 ABC transporter permease -
PO862_RS19615 (PO862_19615) 3962004..3962957 - 954 WP_273884468.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(5-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10880.46 Da        Isoelectric Point: 6.7166

>T273374 WP_273884469.1 NZ_CP118687:c3958258-3957968 [Rhizobium sp. MJ22]
MKTLALSPAAADDIDRIYDYTEEKWGQDQAEDYILALRDDCGALAAQTKRGRKIIGLRSGYTALAFRSHFIIYADTEEAL
IVIRILHRRMNIAAHL

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9020.13 Da        Isoelectric Point: 4.6558

>AT273374 WP_273881409.1 NZ_CP118687:c3958500-3958255 [Rhizobium sp. MJ22]
VAKVVSIRIDDHMEEFIGNQLDQGTYGSADEVIDAGLRLLQREAELAAIEAAIIDGEKSGKPRPFDFDAFMEGKRARRSR
Q

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References